Entity Details

Primary name CREM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ03060
EntryNameCREM_HUMAN
FullNamecAMP-responsive element modulator
TaxID9606
Evidenceevidence at protein level
Length345
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesCREM

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0006006 glucose metabolic process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006631 fatty acid metabolic process
GO:0007165 signal transduction
GO:0007275 multicellular organism development
GO:0007283 spermatogenesis
GO:0008140 cAMP response element binding protein binding
GO:0030154 cell differentiation
GO:0042752 regulation of circadian rhythm
GO:0048384 retinoic acid receptor signaling pathway
GO:0048511 rhythmic process
GO:1990589 ATF4-CREB1 transcription factor complex
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001630 cAMP response element binding (CREB) proteinFamilyFamily
IPR003102 Coactivator CBP, pKIDDomainDomain
IPR004827 Basic-leucine zipper domainDomainDomain

Diseases

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Interactions

50 interactions

InteractorPartnerSourcesPublicationsLink
CREM_HUMANEMP3_HUMANBioGRID, IntAct21988832 details
CREM_HUMANSP100_HUMANBioGRID, IntAct21988832 details
CREM_HUMANC8AP2_HUMANBioGRID, IntAct21988832 details
CREM_HUMANUBC9_HUMANBioGRID, IntAct21988832 details
CREM_HUMANPIAS3_HUMANBioGRID, IntAct21988832 details
CREM_HUMANATX1_HUMANBioGRID, IntAct23275563 details
CREM_HUMANUB2R1_HUMANBioGRID, HPRD, UniProt10373550 details
CREM_HUMANHDAC1_HUMANBioGRID, IntAct17056544 details
CREM_HUMANRHXF2_HUMANBioGRID, IntAct32296183 details
CREM_HUMANMKNK1_HUMANBioGRID, IntAct32296183 details
CREM_HUMANHPCA_HUMANBioGRID, IntAct32296183 details
CREM_HUMANHPCL1_HUMANBioGRID, IntAct32296183 details
CREM_HUMANGLIS2_HUMANBioGRID, IntAct32296183 details
CREM_HUMANVENTX_HUMANBioGRID, IntAct32296183 details
CREM_HUMANNCS1_HUMANBioGRID, IntAct32296183 details
CREM_HUMANNCALD_HUMANBioGRID, IntAct32296183 details
CREM_HUMANRU1C_HUMANBioGRID, IntAct32296183 details
CREM_HUMANRUSC1_HUMANBioGRID, IntAct32296183 details
CREM_HUMANRSMB_HUMANBioGRID, IntAct32296183 details
CREM_HUMANROR2_HUMANBioGRID, IntAct32296183 details
CREM_HUMANUBAP2_HUMANBioGRID, IntAct32296183 details
CREM_HUMANMYOZ3_HUMANBioGRID, IntAct32296183 details
CREM_HUMANBHE40_HUMANBioGRID, IntAct32296183 details
CREM_HUMANPO2F1_HUMANBioGRID, IntAct32296183 details
CREM_HUMANFGFR3_HUMANIntAct32814053 details
CREM_HUMANBAG6_HUMANIntAct32814053 details
CREM_HUMANSPI1_HUMANBioGRID, HPRD7730336 details
CREM_HUMANFHL5_HUMANBioGRID, HPRD10086359 11046156 details
CREM_HUMANTBP_HUMANBioGRID, HPRD10409662 details
CREM_HUMANTAF4_HUMANBioGRID, HPRD10409662 details
CREM_HUMANCSEN_HUMANBioGRID, HPRD11094064 12198160 details
CREM_HUMANMK03_HUMANBioGRID11466319 details
CREM_HUMANCBP_HUMANBioGRID, HPRD9006899 details
CREM_HUMANDNM3L_HUMANBioGRID24952347 details
CREM_HUMANDNM3A_HUMANIntAct21976679 details
CREM_HUMANCREB1_HUMANBioGRID, HPRD, MINT22531917 25609649 7809053 details
CREM_HUMANCR3L4_HUMANBioGRID16595651 details
CREM_HUMANFOXL2_HUMANBioGRID22544055 details
CREM_HUMANCSK21_HUMANHPRD8404858 details
CREM_HUMANCSK22_HUMANHPRD8404858 details
CREM_HUMANCDK1_HUMANHPRD8404858 details
CREM_HUMANCREM_HUMANHPRD8994192 details
CREM_HUMANKPCA_HUMANHPRD8404858 details
CREM_HUMANKC1A_HUMANHPRD8404858 details
CREM_HUMANKAPCA_HUMANHPRD8404858 details
CREM_HUMANGSK3B_HUMANHPRD8404858 details
CREM_HUMANGSK3A_HUMANHPRD8404858 details
CREM_HUMANKCC2D_HUMANHPRD8404858 details
CREM_HUMANCR3L1_HUMANHPRD12805554 details
CREM_HUMANATF1_HUMANHPRD12805554 details