Entity Details

Primary name NSUN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ08J23
EntryNameNSUN2_HUMAN
FullNameRNA cytosine C(5)-methyltransferase NSUN2
TaxID9606
Evidenceevidence at protein level
Length767
SequenceStatuscomplete
DateCreated2007-05-29
DateModified2021-06-02

Ontological Relatives

GenesNSUN2

GO terms

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GOName
GO:0000049 tRNA binding
GO:0001510 RNA methylation
GO:0001701 in utero embryonic development
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005819 spindle
GO:0006400 tRNA modification
GO:0007286 spermatid development
GO:0008168 methyltransferase activity
GO:0010793 regulation of mRNA export from nucleus
GO:0016428 tRNA (cytosine-5-)-methyltransferase activity
GO:0030488 tRNA methylation
GO:0033313 meiotic cell cycle checkpoint signaling
GO:0033391 chromatoid body
GO:0036416 tRNA stabilization
GO:0048820 hair follicle maturation
GO:0051301 cell division
GO:0062152 mRNA (cytidine-5-)-methyltransferase activity
GO:0070062 extracellular exosome
GO:0080009 mRNA methylation
GO:2000736 regulation of stem cell differentiation

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR001678 SAM-dependent methyltransferase RsmB/NOP2-typeDomainDomain
IPR023267 RNA (C5-cytosine) methyltransferaseFamilyFamily
IPR023270 tRNA (C5-cytosine) methyltransferase, NCL1FamilyFamily
IPR029063 S-adenosyl-L-methionine-dependent methyltransferaseFamilyHomologous superfamily

Diseases

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