Entity Details

Primary name TLR6
Entity type gene
Source Source Link

Details

PrimaryID10333
RefseqGeneNG_028087
SymbolTLR6
Nametoll like receptor 6
Chromosome4
Location4p14
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-06-10
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTLR6_HUMAN

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001774 microglial cell activation
GO:0001775 cell activation
GO:0002224 toll-like receptor signaling pathway
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0004888 transmembrane signaling receptor activity
GO:0005102 signaling receptor binding
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007165 signal transduction
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:0010628 positive regulation of gene expression
GO:0030670 phagocytic vesicle membrane
GO:0032717 negative regulation of interleukin-8 production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032755 positive regulation of interleukin-6 production
GO:0034136 negative regulation of toll-like receptor 2 signaling pathway
GO:0034150 toll-like receptor 6 signaling pathway
GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex
GO:0035663 Toll-like receptor 2 binding
GO:0035666 TRIF-dependent toll-like receptor signaling pathway
GO:0038023 signaling receptor activity
GO:0038124 toll-like receptor TLR6:TLR2 signaling pathway
GO:0042496 detection of diacyl bacterial lipopeptide
GO:0042742 defense response to bacterium
GO:0042802 identical protein binding
GO:0043032 positive regulation of macrophage activation
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043235 receptor complex
GO:0043507 positive regulation of JUN kinase activity
GO:0045087 innate immune response
GO:0045121 membrane raft
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0046209 nitric oxide metabolic process
GO:0046982 protein heterodimerization activity
GO:0050135 NAD(P)+ nucleosidase activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
GO:0071221 cellular response to bacterial lipopeptide
GO:0071723 lipopeptide binding
GO:0071726 cellular response to diacyl bacterial lipopeptide
GO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus
GO:1900017 positive regulation of cytokine production involved in inflammatory response
GO:1900227 positive regulation of NLRP3 inflammasome complex assembly
GO:1903223 positive regulation of oxidative stress-induced neuron death
GO:1903428 positive regulation of reactive oxygen species biosynthetic process
GO:1904646 cellular response to amyloid-beta

Diseases

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Interactions

12 interactions