Entity Details

Primary name MALT1
Entity type gene
Source Source Link

Details

PrimaryID10892
RefseqGeneNG_033893
SymbolMALT1
NameMALT1 paracaspase
Chromosome18
Location18q21.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-08-23
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsMALT1_HUMAN

GO terms

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GOName
GO:0001650 fibrillar center
GO:0001923 B-1 B cell differentiation
GO:0002020 protease binding
GO:0002096 polkadots
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002726 positive regulation of T cell cytokine production
GO:0004175 endopeptidase activity
GO:0004197 cysteine-type endopeptidase activity
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006508 proteolysis
GO:0006952 defense response
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:0008233 peptidase activity
GO:0009620 response to fungus
GO:0031398 positive regulation of protein ubiquitination
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0032449 CBM complex
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032743 positive regulation of interleukin-2 production
GO:0032991 protein-containing complex
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042098 T cell proliferation
GO:0042113 B cell activation
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043621 protein self-association
GO:0045087 innate immune response
GO:0048471 perinuclear region of cytoplasm
GO:0050852 T cell receptor signaling pathway
GO:0050856 regulation of T cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051168 nuclear export
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:2000321 positive regulation of T-helper 17 cell differentiation

Diseases

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Interactions

67 interactions

InteractorPartnerSourcesPublicationsLink
MALT1BCL10BioGRID, DIP, HPRD, InnateDB, IntAct, MINT11090634 11262391 14695475 17189706 17948050 18806265 19118383 19279678 19444310 20551178 21157432 21513986 22267217 22528498 22658522 23690623 24130731 25548215 25569716 25748427 27070702 27071417 27113748 27777308 29953499 30279415 31961340 33329596 details
MALT1UBCBioGRID, MINT17948050 31980531 details
MALT1IKBKGBioGRID, IntAct, MINT17948050 18931663 19494296 25748427 27070702 details
MALT1TRAF6BioGRID, HPRD, IntAct, MINT15125833 17948050 19234489 22528498 23264041 25569716 29953499 details
MALT1SUV39H1BioGRID, MINT23455924 details
MALT1KDM1ABioGRID, MINT23455924 details
MALT1CARM1BioGRID, MINT23455924 details
MALT1PRMT6BioGRID, MINT23455924 details
MALT1FEM1CBioGRID, IntAct32296183 details
MALT1FEM1ABioGRID, IntAct32296183 details
MALT1MALT1BioGRID, DIP, HPRD11262391 14695475 19917778 21966355 22158899 22366302 29953499 31961340 details
MALT1DNM2IntAct32814053 details
MALT1GRNIntAct32814053 details
MALT1HSPB1IntAct32814053 details
MALT1PHYHIntAct32814053 details
MALT1PRPS1IntAct32814053 details
MALT1WFS1IntAct32814053 details
MALT1BAG6IntAct32814053 details
MALT1KLF11IntAct32814053 details
MALT1KIF1BIntAct32814053 details
MALT1SPRED1IntAct32814053 details
MALT1ATXN3BioGRID, IntAct29111377 32814053 details
MALT1TRAF2BioGRID, HPRD15125833 19234489 details
MALT1RELBBioGRID21873235 31961340 details
MALT1USP2BioGRID23264041 28052131 details
MALT1HECTD3BioGRID23358872 details
MALT1UBE2V2BioGRID14695475 details
MALT1UBE2NBioGRID14695475 details
MALT1RBCK1BioGRID26525107 33329596 details
MALT1SQSTM1BioGRID, HPRD, MINT16874300 details
MALT1VHLIntAct17353931 details
MALT1PRKCQBioGRID, MINT17363905 details
MALT1TAB2BioGRID, MINT17948050 25748427 details
MALT1MAP3K7BioGRID, MINT17948050 25748427 details
MALT1CARD11BioGRID, IntAct, MINT17948050 22528498 23322406 25748427 31961340 33329596 details
MALT1COPS5BioGRID, MINT19444310 details
MALT1GPS1BioGRID, MINT19444310 details
MALT1CASP8InnateDB22267217 details
MALT1SHARPINBioGRID, IntAct27070702 33329596 details
MALT1PRKCDBioGRID, IntAct22528498 details
MALT1CSNK1A1BioGRID, DIP19118383 20551178 25088585 details
MALT1TRAF3IntAct19917778 details
MALT1NFKBIABioGRID20551178 details
MALT1CAMK2GBioGRID21513986 details
MALT1DIABLOBioGRID19234489 details
MALT1DAB2BioGRID22323290 details
MALT1USP9XBioGRID23690623 details
MALT1STUB1BioGRID23322406 details
MALT1RNF31BioGRID24491438 33329596 details
MALT1TNFAIP3BioGRID24491438 details
MALT1CARD14BioGRID27071417 27113748 details
MALT1GRK2BioGRID31961340 details
MALT1CYLDBioGRID33329596 details
MALT1OTULINBioGRID33329596 details
MALT1UBE2G2BioGRID, IntAct17353931 details
MALT1CARD9InnateDB22267217 details
MALT1PYCARDInnateDB22267217 details
MALT1BIRC3IntAct27070702 details
MALT1TRIB1BioGRID, IntAct28514442 details
MALT1IKBKBBioGRID, DIP19118383 details
MALT1XPO1BioGRID26673895 details
MALT1PLEKHA4BioGRID31091453 details
MALT1KIF23BioGRID31586073 details
MALT1BRD1BioGRID31753913 details
MALT1NPM1BioGRID34079125 details
MALT1HNRNPLBioGRID28611215 details
MALT1APEX1BioGRID28986522 details