Entity Details

Primary name FLII_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13045
EntryNameFLII_HUMAN
FullNameProtein flightless-1 homolog
TaxID9606
Evidenceevidence at protein level
Length1269
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesFLII

GO terms

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GOName
GO:0003779 actin binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005903 brush border
GO:0005925 focal adhesion
GO:0007275 multicellular organism development
GO:0008154 actin polymerization or depolymerization
GO:0015629 actin cytoskeleton
GO:0030239 myofibril assembly
GO:0034451 centriolar satellite
GO:0051014 actin filament severing
GO:0051015 actin filament binding
GO:0051016 barbed-end actin filament capping

Subcellular Location

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Subcellular Location
Cell junction
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001611 Leucine-rich repeatRepeatRepeat
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR007122 Villin/GelsolinFamilyFamily
IPR007123 Gelsolin-like domainDomainDomain
IPR029006 ADF-H/Gelsolin-like domain superfamilyFamilyHomologous superfamily
IPR029919 Protein flightless-1FamilyFamily
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily

Diseases

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