Entity Details

Primary name DEFB1
Entity type gene
Source Source Link

Details

PrimaryID1672
RefseqGene
SymbolDEFB1
Namedefensin beta 1
Chromosome8
Location8p23.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-06
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsDEFB1_HUMAN

GO terms

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GOName
GO:0002227 innate immune response in mucosa
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005796 Golgi lumen
GO:0006935 chemotaxis
GO:0006955 immune response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0009617 response to bacterium
GO:0019730 antimicrobial humoral response
GO:0019731 antibacterial humoral response
GO:0019898 extrinsic component of membrane
GO:0019933 cAMP-mediated signaling
GO:0031731 CCR6 chemokine receptor binding
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0042742 defense response to bacterium
GO:0042802 identical protein binding
GO:0045087 innate immune response
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
GO:0060474 positive regulation of flagellated sperm motility involved in capacitation
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0070062 extracellular exosome
GO:0097225 sperm midpiece
GO:1990742 microvesicle

Diseases

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Interactions

13 interactions

InteractorPartnerSourcesPublicationsLink
DEFB1MAP4K2BioGRID, MINT21900206 details
DEFB1ASPHBioGRID, IntAct32296183 details
DEFB1VIMHPRD15383276 details
DEFB1RIF1HPRD15383276 details
DEFB1CCR6HPRD12149255 details
DEFB1FBXW5BioGRID, IntAct28514442 details
DEFB1FAM172ABioGRID, IntAct28514442 details
DEFB1PM20D2BioGRID, IntAct28514442 details
DEFB1PMPCABioGRID, IntAct28514442 details
DEFB1NMT1BioGRID, IntAct28514442 details
DEFB1IDEBioGRID, IntAct28514442 details
DEFB1PMPCBBioGRID, IntAct28514442 details
DEFB1NMT2BioGRID, IntAct28514442 details