Entity Details

Primary name DUSP3
Entity type gene
Source Source Link

Details

PrimaryID1845
RefseqGene
SymbolDUSP3
Namedual specificity phosphatase 3
Chromosome17
Location17q21.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-12-14
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsDUS3_HUMAN

GO terms

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GOName
GO:0000188 obsolete inactivation of MAPK activity
GO:0001772 immunological synapse
GO:0004725 protein tyrosine phosphatase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0008092 cytoskeletal protein binding
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0016311 dephosphorylation
GO:0016791 phosphatase activity
GO:0019901 protein kinase binding
GO:0030336 negative regulation of cell migration
GO:0030971 receptor tyrosine kinase binding
GO:0033549 MAP kinase phosphatase activity
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0043409 negative regulation of MAPK cascade
GO:0045931 positive regulation of mitotic cell cycle
GO:0046329 negative regulation of JNK cascade
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0050868 negative regulation of T cell activation
GO:0050922 negative regulation of chemotaxis
GO:0051893 regulation of focal adhesion assembly
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity
GO:0120183 positive regulation of focal adhesion disassembly
GO:1990264 peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity
GO:1990782 protein tyrosine kinase binding

Diseases

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Interactions

46 interactions

InteractorPartnerSourcesPublicationsLink
DUSP3BNIP3LBioGRID, IntAct21988832 details
DUSP3NEUROD1BioGRID, IntAct21988832 details
DUSP3CASKBioGRID, IntAct21988832 details
DUSP3MAPK3BioGRID, HPRD, MINT10224087 12840032 details
DUSP3MAPK1BioGRID, HPRD, MINT10224087 12840032 details
DUSP3MEOX1BioGRID, IntAct32296183 details
DUSP3EGFRBioGRID1281549 details
DUSP3APPBioGRID21832049 details
DUSP3MCCIntAct17353931 details
DUSP3HLA-BIntAct17353931 details
DUSP3PDGFAHPRD1281549 details
DUSP3ZAP70HPRD12447358 details
DUSP3MAP2K2HPRD10224087 details
DUSP3STAT1HPRD11238845 details
DUSP3SYKHPRD12447358 details
DUSP3EGFHPRD1281549 details
DUSP3FGF7HPRD1281549 details
DUSP3HSCBBioGRID, IntAct28380382 details
DUSP3GTF2E2BioGRID, IntAct28514442 details
DUSP3SNRNP27BioGRID, IntAct28514442 details
DUSP3DNAAF8BioGRID, IntAct28514442 details
DUSP3FGBBioGRID, IntAct28514442 details
DUSP3ARL6IP6BioGRID, IntAct26186194 28514442 details
DUSP3ERLIN1BioGRID, IntAct28514442 details
DUSP3TUFMBioGRID, IntAct30021884 details
DUSP3ERLIN2BioGRID, IntAct22119785 details
DUSP3DUSP1BioGRID27432908 details
DUSP3DUSP12BioGRID27432908 details
DUSP3DUSP13BioGRID27432908 details
DUSP3DUSP2BioGRID27432908 details
DUSP3DUSP3BioGRID27432908 details
DUSP3CLEC1BBioGRID27432908 details
DUSP3NT5C2BioGRID27432908 details
DUSP3DOCK11BioGRID27432908 details
DUSP3HOOK3BioGRID27432908 details
DUSP3RPIABioGRID27432908 details
DUSP3UGT8BioGRID27432908 details
DUSP3COPG1BioGRID28675297 details
DUSP3DUSP14BioGRID28675297 details
DUSP3EIF2B3BioGRID28675297 details
DUSP3FASNBioGRID28675297 details
DUSP3LRPPRCBioGRID28675297 details
DUSP3PSMD2BioGRID28675297 details
DUSP3PLEKHA4BioGRID31091453 details
DUSP3ELAVL1BioGRID19322201 details
DUSP3AGO2BioGRID29955039 details