Entity Details

Primary name TF2H2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13888
EntryNameTF2H2_HUMAN
FullNameGeneral transcription factor IIH subunit 2
TaxID9606
Evidenceevidence at protein level
Length395
SequenceStatuscomplete
DateCreated2001-10-18
DateModified2021-06-02

Ontological Relatives

GenesGTF2H2

GO terms

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GOName
GO:0000438 core TFIIH complex portion of holo TFIIH complex
GO:0000439 transcription factor TFIIH core complex
GO:0000717 nucleotide-excision repair, DNA duplex unwinding
GO:0002031 G protein-coupled receptor internalization
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005669 transcription factor TFIID complex
GO:0005675 transcription factor TFIIH holo complex
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006289 nucleotide-excision repair
GO:0006293 nucleotide-excision repair, preincision complex stabilization
GO:0006294 nucleotide-excision repair, preincision complex assembly
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006361 transcription initiation from RNA polymerase I promoter
GO:0006363 termination of RNA polymerase I transcription
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006370 7-methylguanosine mRNA capping
GO:0008270 zinc ion binding
GO:0009411 response to UV
GO:0016032 viral process
GO:0016251 RNA polymerase II general transcription initiation factor activity
GO:0016607 nuclear speck
GO:0033683 nucleotide-excision repair, DNA incision
GO:0047485 protein N-terminus binding
GO:0070911 global genome nucleotide-excision repair
GO:1905776 positive regulation of DNA helicase activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002035 von Willebrand factor, type ADomainDomain
IPR004595 TFIIH C1-like domainDomainDomain
IPR007198 Ssl1-likeDomainDomain
IPR012170 TFIIH subunit Ssl1/p44FamilyFamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036465 von Willebrand factor A-like domain superfamilyFamilyHomologous superfamily

Diseases

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