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Entity Details
Primary name
FHIT
Entity type
gene
Source
Source Link
Details
PrimaryID
2272
RefseqGene
NG_007551
Symbol
FHIT
Name
fragile histidine triad diadenosine triphosphatase
Chromosome
3
Location
3p14.2
TaxID
9606
Status
live
SourceGenome
genomic
SourceOrigin
natural
CreationDate
1998-08-27
ModificationDate
2021-06-11
Ontological Relatives
UniProt IDs
FHIT_HUMAN
GO terms
Show/Hide Table
GO
Name
GO:0000166
nucleotide binding
GO:0001650
fibrillar center
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005739
mitochondrion
GO:0005829
cytosol
GO:0005886
plasma membrane
GO:0006163
purine nucleotide metabolic process
GO:0015964
diadenosine triphosphate catabolic process
GO:0031625
ubiquitin protein ligase binding
GO:0032435
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042802
identical protein binding
GO:0047710
bis(5'-adenosyl)-triphosphatase activity
GO:0072332
intrinsic apoptotic signaling pathway by p53 class mediator
Diseases
Show/Hide Table
Interactions
16 interactions
Interactor
Partner
Sources
Publications
Link
FHIT
FHIT
BioGRID, DIP, HPRD, IntAct, UniProt
16189514
18077326
24722188
25416956
27107012
31515488
32296183
9261067
9576908
details
FHIT
TRIM23
BioGRID, IntAct
21988832
details
FHIT
RAB40B
BioGRID, IntAct
21988832
details
FHIT
REL
BioGRID, IntAct
24722188
details
FHIT
DDIT4L
BioGRID, IntAct
32296183
details
FHIT
CTNNB1
BioGRID, DIP
18077326
details
FHIT
UBE2I
BioGRID, HPRD
11085938
details
FHIT
LEF1
BioGRID, DIP
18077326
details
FHIT
MDM2
BioGRID
15313915
details
FHIT
GSN
HPRD
12833632
details
FHIT
SRC
HPRD
15835917
details
FHIT
FDXR
HPRD
19004824
details
FHIT
HSPD1
HPRD
19004824
details
FHIT
ARHGAP19
BioGRID, IntAct
28514442
details
FHIT
MTMR6
BioGRID, IntAct
28514442
details
FHIT
RABL2A
BioGRID
28514442
details
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