Entity Details

Primary name DKK1
Entity type gene
Source Source Link

Details

PrimaryID22943
RefseqGene
SymbolDKK1
Namedickkopf WNT signaling pathway inhibitor 1
Chromosome10
Location10q21.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-09-01
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsDKK1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0002090 regulation of receptor internalization
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0007611 learning or memory
GO:0008083 growth factor activity
GO:0010628 positive regulation of gene expression
GO:0010942 positive regulation of cell death
GO:0016055 Wnt signaling pathway
GO:0030178 negative regulation of Wnt signaling pathway
GO:0030279 negative regulation of ossification
GO:0031901 early endosome membrane
GO:0032091 negative regulation of protein binding
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0039706 co-receptor binding
GO:0042662 negative regulation of mesodermal cell fate specification
GO:0042663 regulation of endodermal cell fate specification
GO:0043066 negative regulation of apoptotic process
GO:0043507 positive regulation of JUN kinase activity
GO:0045813 positive regulation of Wnt signaling pathway, calcium modulating pathway
GO:0048019 receptor antagonist activity
GO:0050750 low-density lipoprotein particle receptor binding
GO:0060173 limb development
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0090082 positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090647 modulation of age-related behavioral decline
GO:0098883 synapse pruning
GO:1901216 positive regulation of neuron death
GO:1901296 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
GO:1902949 positive regulation of tau-protein kinase activity
GO:1904338 regulation of dopaminergic neuron differentiation
GO:1904723 negative regulation of Wnt-Frizzled-LRP5/6 complex assembly
GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway
GO:2000726 negative regulation of cardiac muscle cell differentiation

Diseases

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