Entity Details

Primary name PPP1R15A
Entity type gene
Source Source Link

Details

PrimaryID23645
RefseqGene
SymbolPPP1R15A
Nameprotein phosphatase 1 regulatory subunit 15A
Chromosome19
Location19q13.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-02
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPR15A_HUMAN

GO terms

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GOName
GO:0000164 protein phosphatase type 1 complex
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0008157 protein phosphatase 1 binding
GO:0016020 membrane
GO:0019888 protein phosphatase regulator activity
GO:0019901 protein kinase binding
GO:0032058 positive regulation of translational initiation in response to stress
GO:0032515 negative regulation of phosphoprotein phosphatase activity
GO:0032516 positive regulation of phosphoprotein phosphatase activity
GO:0034976 response to endoplasmic reticulum stress
GO:0035308 negative regulation of protein dephosphorylation
GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070972 protein localization to endoplasmic reticulum
GO:0072542 protein phosphatase activator activity
GO:1902310 positive regulation of peptidyl-serine dephosphorylation
GO:1903898 negative regulation of PERK-mediated unfolded protein response
GO:1903917 positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

Diseases

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Interactions

141 interactions

InteractorPartnerSourcesPublicationsLink
PPP1R15AZNF512BBioGRID, MINT15231748 details
PPP1R15APPP1CABioGRID, HPRD, IntAct, MINT12016208 12724406 15231748 26095357 29109149 details
PPP1R15ABCAR1BioGRID, HPRD, IntAct16169070 details
PPP1R15APOU3F3HPRD, IntAct16169070 details
PPP1R15APPP1R1ABioGRID, HPRD, IntAct11564868 details
PPP1R15ACTBP2BioGRID, IntAct21988832 details
PPP1R15AKMT2ABioGRID, HPRD10490642 details
PPP1R15ABAG1BioGRID, HPRD12724406 details
PPP1R15ASMARCB1BioGRID, HPRD10490642 12016208 details
PPP1R15ATSNBioGRID, HPRD10434033 details
PPP1R15ALYNBioGRID, HPRD11517336 details
PPP1R15AHABP4BioGRID, HPRD16455055 details
PPP1R15ACUEDC2BioGRID18362886 details
PPP1R15ARAD21BioGRID22145905 details
PPP1R15ASMAD7BioGRID14718519 details
PPP1R15AKIF3AHPRD10631107 details
PPP1R15AMYCIntAct20195357 details
PPP1R15APPP1CBBioGRID, IntAct12016208 29109149 details
PPP1R15AHSPA8BioGRID, IntAct12724406 29109149 details
PPP1R15AHSPA1AHPRD, IntAct12724406 29109149 details
PPP1R15ATARDBPIntAct29109149 details
PPP1R15AEIF2S1BioGRID, HPRD, IntAct12556489 26095357 29109149 details
PPP1R15APRKCEIntAct29109149 details
PPP1R15APPP1CCBioGRID12016208 14670976 details
PPP1R15AIKBKBBioGRID18362886 details
PPP1R15ACAND1BioGRID, IntAct21145461 details
PPP1R15ACOPS5BioGRID, IntAct21145461 details
PPP1R15ACUL3BioGRID, IntAct21145461 details
PPP1R15ACEP290IntAct29109149 details
PPP1R15ATRAFD1IntAct29109149 details
PPP1R15AGTSE1IntAct29109149 details
PPP1R15AHSPA2IntAct29109149 details
PPP1R15AHADHAIntAct29109149 details
PPP1R15ATRIM28IntAct29109149 details
PPP1R15AEEF2IntAct29109149 details
PPP1R15ATUBB8IntAct29109149 details
PPP1R15AACTBL2IntAct29109149 details
PPP1R15ACOPB1IntAct29109149 details
PPP1R15AHSPA5IntAct29109149 details
PPP1R15AKRT9IntAct29109149 details
PPP1R15AGTPBP1IntAct29109149 details
PPP1R15AALDH18A1IntAct29109149 details
PPP1R15AKRT10IntAct29109149 details
PPP1R15ACLNS1AIntAct29109149 details
PPP1R15AKIF11IntAct29109149 details
PPP1R15AAIFM1IntAct29109149 details
PPP1R15AKRT2IntAct29109149 details
PPP1R15ATRAP1IntAct29109149 details
PPP1R15AAKAP8LIntAct29109149 details
PPP1R15ADAP3IntAct29109149 details
PPP1R15ACCT8IntAct29109149 details
PPP1R15APPP2R2AIntAct29109149 details
PPP1R15ASTOML2IntAct29109149 details
PPP1R15ADDX3XIntAct29109149 details
PPP1R15ACHEK1IntAct29109149 details
PPP1R15AHSPA1BIntAct29109149 details
PPP1R15AYME1L1IntAct29109149 details
PPP1R15ASNX18IntAct29109149 details
PPP1R15AHSPH1IntAct29109149 details
PPP1R15AMAGED4IntAct29109149 details
PPP1R15AMAGED4BIntAct29109149 details
PPP1R15ANUFIP1IntAct29109149 details
PPP1R15ADDX52IntAct29109149 details
PPP1R15AZNF629IntAct29109149 details
PPP1R15ALAS1LIntAct29109149 details
PPP1R15AOBI1IntAct29109149 details
PPP1R15AGTF3C3IntAct29109149 details
PPP1R15ATUBB2BIntAct29109149 details
PPP1R15AESYT2IntAct29109149 details
PPP1R15AMAGED2IntAct29109149 details
PPP1R15ATARS2IntAct29109149 details
PPP1R15AGTF3C4IntAct29109149 details
PPP1R15ASLC25A13IntAct29109149 details
PPP1R15ASLFN11IntAct29109149 details
PPP1R15ATHAP4IntAct29109149 details
PPP1R15ATMEM183AIntAct29109149 details
PPP1R15ANACAIntAct29109149 details
PPP1R15APSMC5IntAct29109149 details
PPP1R15ANOM1IntAct29109149 details
PPP1R15ASSRP1IntAct29109149 details
PPP1R15AKRT1IntAct29109149 details
PPP1R15AIRS4IntAct29109149 details
PPP1R15ATOMM70IntAct29109149 details
PPP1R15AABCF1IntAct29109149 details
PPP1R15ANCAPH2IntAct29109149 details
PPP1R15ACBX4IntAct29109149 details
PPP1R15APSMC6IntAct29109149 details
PPP1R15AKNOP1IntAct29109149 details
PPP1R15APARP1IntAct29109149 details
PPP1R15AHNRNPFIntAct29109149 details
PPP1R15AHNRNPA2B1IntAct29109149 details
PPP1R15AERAL1IntAct29109149 details
PPP1R15ANOP56IntAct29109149 details
PPP1R15ATIMM50IntAct29109149 details
PPP1R15ACSNK2A2IntAct29109149 details
PPP1R15ADNAJA2IntAct29109149 details
PPP1R15ASMN1IntAct29109149 details
PPP1R15ASMN2IntAct29109149 details
PPP1R15AWDR5IntAct29109149 details
PPP1R15AHNRNPMIntAct29109149 details
PPP1R15AIPO5IntAct29109149 details
PPP1R15ACNPIntAct29109149 details
PPP1R15ARNF138IntAct29109149 details
PPP1R15APRPSAP2IntAct29109149 details
PPP1R15ATCP1IntAct29109149 details
PPP1R15ATRIP13IntAct29109149 details
PPP1R15AEIF2S3IntAct29109149 details
PPP1R15AMYO1CIntAct29109149 details
PPP1R15APRC1IntAct29109149 details
PPP1R15ANR2F1IntAct29109149 details
PPP1R15AABCE1IntAct29109149 details
PPP1R15AALDOAIntAct29109149 details
PPP1R15APRPSAP1IntAct29109149 details
PPP1R15ACKAP4IntAct29109149 details
PPP1R15APSMD11IntAct29109149 details
PPP1R15AHNRNPH1IntAct29109149 details
PPP1R15AATAD3AIntAct29109149 details
PPP1R15ASPTLC1IntAct29109149 details
PPP1R15AH2AC13IntAct29109149 details
PPP1R15AH2AC15IntAct29109149 details
PPP1R15AH2AC16IntAct29109149 details
PPP1R15AH2AC17IntAct29109149 details
PPP1R15AH2AC11IntAct29109149 details
PPP1R15ADUSP11IntAct29109149 details
PPP1R15AHADHBIntAct29109149 details
PPP1R15ASGPL1IntAct29109149 details
PPP1R15APDCD2IntAct29109149 details
PPP1R15AZNF281IntAct29109149 details
PPP1R15ALIMA1IntAct29109149 details
PPP1R15AMICU1IntAct29109149 details
PPP1R15AKEAP1IntAct29109149 details
PPP1R15ADNAJA3IntAct29109149 details
PPP1R15APLEKHA1BioGRID, IntAct28514442 details
PPP1R15ABBXBioGRID, IntAct28514442 details
PPP1R15AMINK1BioGRID, IntAct28514442 details
PPP1R15APWWP3ABioGRID, IntAct28514442 details
PPP1R15AZNF92BioGRID, IntAct28514442 details
PPP1R15APOP4BioGRID, IntAct28514442 details
PPP1R15APLECBioGRID, IntAct30021884 details
PPP1R15APPP1R15AIntAct26095357 details
PPP1R15ADDX58BioGRID32513696 details