Entity Details

Primary name ERG1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14534
EntryNameERG1_HUMAN
FullNameSqualene monooxygenase
TaxID9606
Evidenceevidence at protein level
Length574
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesSQLE

GO terms

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GOName
GO:0004506 squalene monooxygenase activity
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006695 cholesterol biosynthetic process
GO:0006725 cellular aromatic compound metabolic process
GO:0008203 cholesterol metabolic process
GO:0010033 response to organic substance
GO:0016021 integral component of membrane
GO:0016126 sterol biosynthetic process
GO:0019216 regulation of lipid metabolic process
GO:0042127 regulation of cell population proliferation
GO:0043231 intracellular membrane-bounded organelle
GO:0071949 FAD binding
GO:0140042 lipid droplet formation

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Microsome membrane

Domains

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DomainNameCategoryType
IPR013698 Squalene epoxidaseDomainDomain
IPR036188 FAD/NAD(P)-binding domain superfamilyFamilyHomologous superfamily
IPR040125 Squalene monooxygenaseFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00735 NaftifineDrugbanksmall molecule
DB00857 TerbinafineDrugbanksmall molecule
DB01091 ButenafineDrugbanksmall molecule
DB08846 Ellagic acidDrugbanksmall molecule