Entity Details

Primary name PTGR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14914
EntryNamePTGR1_HUMAN
FullNameProstaglandin reductase 1
TaxID9606
Evidenceevidence at protein level
Length329
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesPTGR1

GO terms

Show/Hide Table
GOName
GO:0005737 cytoplasm
GO:0006691 leukotriene metabolic process
GO:0006693 prostaglandin metabolic process
GO:0035798 2-alkenal reductase (NADP+) activity
GO:0036102 leukotriene B4 metabolic process
GO:0036132 13-prostaglandin reductase activity
GO:0036185 13-lipoxin reductase activity
GO:0047522 15-oxoprostaglandin 13-oxidase activity
GO:0070062 extracellular exosome
GO:0097257 leukotriene B4 12-hydroxy dehydrogenase activity
GO:0097327 response to antineoplastic agent
GO:2001302 lipoxin A4 metabolic process

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR011032 GroES-like superfamilyFamilyHomologous superfamily
IPR013149 Alcohol dehydrogenase, C-terminalDomainDomain
IPR014190 Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductaseFamilyFamily
IPR020843 Polyketide synthase, enoylreductase domainDomainDomain
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily
IPR041694 Oxidoreductase, N-terminal domainDomainDomain

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB03461 Nicotinamide adenine dinucleotide phosphateDrugbanksmall molecule
DB04066 p-Coumaric acidDrugbanksmall molecule
DB07177 (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACIDDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PTGR1_HUMANJPH3_HUMANIntAct32814053 details
PTGR1_HUMANOBI1_HUMANIntAct31413325 details