Entity Details

Primary name NFAC4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14934
EntryNameNFAC4_HUMAN
FullNameNuclear factor of activated T-cells, cytoplasmic 4
TaxID9606
Evidenceevidence at protein level
Length902
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesNFATC4

GO terms

Show/Hide Table
GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001569 branching involved in blood vessel morphogenesis
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006954 inflammatory response
GO:0007507 heart development
GO:0007616 long-term memory
GO:0008134 transcription factor binding
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016607 nuclear speck
GO:0030178 negative regulation of Wnt signaling pathway
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway
GO:0032091 negative regulation of protein binding
GO:0032760 positive regulation of tumor necrosis factor production
GO:0033173 calcineurin-NFAT signaling cascade
GO:0034644 cellular response to UV
GO:0035562 negative regulation of chromatin binding
GO:0042975 peroxisome proliferator activated receptor binding
GO:0043524 negative regulation of neuron apoptotic process
GO:0045333 cellular respiration
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050774 negative regulation of dendrite morphogenesis
GO:0051145 smooth muscle cell differentiation
GO:0055001 muscle cell development
GO:0060291 long-term synaptic potentiation
GO:0071285 cellular response to lithium ion
GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000297 negative regulation of synapse maturation
GO:2001235 positive regulation of apoptotic signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR002909 IPT domainDomainDomain
IPR008366 Nuclear factor of activated T cells (NFAT)FamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR011539 Rel homology domain (RHD), DNA-binding domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR032397 Rel homology dimerisation domainDomainDomain
IPR037059 Rel homology domain (RHD), DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table