Entity Details

Primary name GTF2H2
Entity type gene
Source Source Link

Details

PrimaryID2966
RefseqGene
SymbolGTF2H2
Namegeneral transcription factor IIH subunit 2
Chromosome5
Location5q13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTF2H2_HUMAN

GO terms

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GOName
GO:0000438 core TFIIH complex portion of holo TFIIH complex
GO:0000439 transcription factor TFIIH core complex
GO:0000717 nucleotide-excision repair, DNA duplex unwinding
GO:0002031 G protein-coupled receptor internalization
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005669 transcription factor TFIID complex
GO:0005675 transcription factor TFIIH holo complex
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006289 nucleotide-excision repair
GO:0006293 nucleotide-excision repair, preincision complex stabilization
GO:0006294 nucleotide-excision repair, preincision complex assembly
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006361 transcription initiation from RNA polymerase I promoter
GO:0006363 termination of RNA polymerase I transcription
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006370 7-methylguanosine mRNA capping
GO:0008270 zinc ion binding
GO:0009411 response to UV
GO:0016032 viral process
GO:0016251 RNA polymerase II general transcription initiation factor activity
GO:0016607 nuclear speck
GO:0033683 nucleotide-excision repair, DNA incision
GO:0047485 protein N-terminus binding
GO:0070911 global genome nucleotide-excision repair
GO:1905776 positive regulation of DNA helicase activity

Diseases

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Interactions

34 interactions

InteractorPartnerSourcesPublicationsLink
GTF2H2ERCC8BioGRID, HPRD, IntAct7664335 details
GTF2H2GTF2H1BioGRID, HPRD, IntAct11062469 19934020 21988832 24981860 26340423 26344197 28977422 8194529 8652557 9130708 details
GTF2H2CDK7BioGRID, HPRD, IntAct11062469 17643375 19934020 23602568 28977422 29568061 9130708 details
GTF2H2GTF2H5BioGRID, DIP, HPRD, IntAct11062469 15220921 16669699 19172752 24981860 26496610 28514442 details
GTF2H2ERCC3BioGRID, HPRD, IntAct15220921 17643375 19934020 24981860 26340423 26344197 28514442 28977422 8194529 9118947 details
GTF2H2GTF2H3BioGRID, IntAct, MINT12080057 15790571 21157430 22939629 24981860 26340423 26344197 28514442 28977422 details
GTF2H2GTF2H4BioGRID, DIP, IntAct11062469 19172752 19934020 22939629 24981860 26340423 26344197 28977422 details
GTF2H2ERCC2BioGRID, DIP, HPRD, IntAct11062469 12820975 19934020 26340423 27193682 9771713 details
GTF2H2MNAT1BioGRID26340423 8692842 details
GTF2H2ARBioGRID21157430 details
GTF2H2SRA1BioGRID20398657 details
GTF2H2DNMT3LBioGRID24952347 details
GTF2H2ERRFI1BioGRID20351267 details
GTF2H2GTF2E1BioGRID25492609 details
GTF2H2CCNHBioGRID, IntAct11062469 19934020 26340423 details
GTF2H2COPS2BioGRID17438371 details
GTF2H2FGL1BioGRID, IntAct26186194 28514442 details
GTF2H2ZNF232BioGRID, IntAct28514442 details
GTF2H2RNF135BioGRID, IntAct28514442 details
GTF2H2LRRK2IntAct31046837 details
GTF2H2ENGBioGRID, UniProt31540324 details
GTF2H2H1-2BioGRID, MINT24981860 details
GTF2H2LHX6BioGRID26186194 details
GTF2H2ARHGAP25BioGRID26186194 details
GTF2H2NFATC2BioGRID27637333 details
GTF2H2ESR2BioGRID29509190 details
GTF2H2ATG16L1BioGRID30196744 details
GTF2H2NR2C2BioGRID30463901 details
GTF2H2PLEKHA4BioGRID31091453 details
GTF2H2NUPR1BioGRID32780723 details
GTF2H2GTF2F1BioGRID24981860 details
GTF2H2GTF2H2CBioGRID24981860 details
GTF2H2KLF9IntAct19934020 details
GTF2H2HNRNPLBioGRID28611215 details