Entity Details

Primary name LOX
Entity type gene
Source Source Link

Details

PrimaryID4015
RefseqGeneNG_008722
SymbolLOX
Namelysyl oxidase
Chromosome5
Location5q23.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-03-24
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsLYOX_HUMAN

GO terms

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GOName
GO:0001649 osteoblast differentiation
GO:0001932 regulation of protein phosphorylation
GO:0004720 protein-lysine 6-oxidase activity
GO:0005507 copper ion binding
GO:0005518 collagen binding
GO:0005576 extracellular region
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0006464 cellular protein modification process
GO:0007507 heart development
GO:0010468 regulation of gene expression
GO:0016202 regulation of striated muscle tissue development
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
GO:0018057 peptidyl-lysine oxidation
GO:0030198 extracellular matrix organization
GO:0030199 collagen fibril organization
GO:0030282 bone mineralization
GO:0030324 lung development
GO:0031012 extracellular matrix
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway
GO:0035905 ascending aorta development
GO:0035906 descending aorta development
GO:0042060 wound healing
GO:0042493 response to drug
GO:0042981 regulation of apoptotic process
GO:0043491 protein kinase B signaling
GO:0045652 regulation of megakaryocyte differentiation
GO:0046716 muscle cell cellular homeostasis
GO:0048251 elastic fiber assembly
GO:0048514 blood vessel morphogenesis
GO:0048545 response to steroid hormone
GO:0060326 cell chemotaxis
GO:0061448 connective tissue development
GO:0071897 DNA biosynthetic process
GO:1900120 regulation of receptor binding
GO:1903010 regulation of bone development
GO:1990869 cellular response to chemokine
GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway

Diseases

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Interactions

43 interactions

InteractorPartnerSourcesPublicationsLink
LOXEFEMP2DIP, matrixdb19570982 19855011 details
LOXELNBioGRID, HPRD, matrixdb12686141 19570982 6912069 details
LOXFBN1matrixdb19570982 details
LOXFBLN5matrixdb19570982 25118846 details
LOXCOL1A1matrixdb21690299 details
LOXCOL1A2matrixdb21690299 details
LOXCOL3A1matrixdb21690299 details
LOXFN1matrixdb21690299 details
LOXPTPRKBioGRID, matrixdb21690299 details
LOXTFAP2CIntAct24835590 details
LOXGATAD2Bmatrixdb25118846 details
LOXMEMO1matrixdb25118846 details
LOXMDC1matrixdb25118846 details
LOXSOS2matrixdb25118846 details
LOXPA2G4matrixdb25118846 details
LOXUXTmatrixdb28106301 details
LOXADAMTSL4matrixdb29758265 details
LOXDHDDSBioGRID, HPRD15110773 details
LOXH1-1BioGRID12686141 details
LOXH2BC21BioGRID12686141 details
LOXRAF1BioGRID22438909 details
LOXLOXHPRD15110773 details
LOXHSPA1Amatrixdb21536655 details
LOXHSPA1Bmatrixdb21536655 details
LOXATP7Amatrixdb31932435 details
LOXATOX1matrixdb31932435 details
LOXSH3KBP1BioGRID24167568 details
LOXCD2APBioGRID24167568 details
LOXCBLBioGRID24167568 details
LOXDPTHPRD8082810 details
LOXH1-5HPRD12686141 details
LOXH2BC11HPRD12686141 details
LOXMYCIntAct21150319 details
LOXIQCB1BioGRID, IntAct21565611 details
LOXMAD2L2BioGRID, UniProt29656893 details
LOXSOX2BioGRID, MINT23667531 details
LOXRNF4BioGRID29180619 details
LOXAGPSBioGRID31536960 details
LOXATP6V1ABioGRID31536960 details
LOXNDUFB8BioGRID31536960 details
LOXJTBBioGRID31536960 details
LOXATP5F1CBioGRID31536960 details
LOXKIF20ABioGRID31586073 details