Entity Details

Primary name MITF
Entity type gene
Source Source Link

Details

PrimaryID4286
RefseqGeneNG_011631
SymbolMITF
Namemelanocyte inducing transcription factor
Chromosome3
Location3p13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-05-16
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsMITF_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0010628 positive regulation of gene expression
GO:0030316 osteoclast differentiation
GO:0030318 melanocyte differentiation
GO:0030336 negative regulation of cell migration
GO:0032991 protein-containing complex
GO:0042127 regulation of cell population proliferation
GO:0043010 camera-type eye development
GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process
GO:0045165 cell fate commitment
GO:0045670 regulation of osteoclast differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046849 bone remodeling
GO:0046983 protein dimerization activity
GO:0065003 protein-containing complex assembly
GO:0070888 E-box binding
GO:2000144 positive regulation of DNA-templated transcription, initiation
GO:2001141 regulation of RNA biosynthetic process

Diseases

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Interactions

45 interactions

InteractorPartnerSourcesPublicationsLink
MITFHK3BioGRID, IntAct21988832 details
MITFSTUB1BioGRID, IntAct21988832 details
MITFEBPBioGRID, IntAct21988832 details
MITFADRB2BioGRID, MINT28298427 details
MITFLEF1BioGRID, HPRD12032083 12048204 details
MITFPIAS3BioGRID, HPRD11709556 16029420 details
MITFPATZ1BioGRID, HPRD11751862 details
MITFUBE2IBioGRID, HPRD10694430 16029420 details
MITFSPI1BioGRID, HPRD9918847 details
MITFPAX6BioGRID, HPRD11350962 details
MITFPIAS1BioGRID16029420 details
MITFPIAS2BioGRID16029420 details
MITFPSMD14BioGRID20058232 details
MITFMARK3BioGRID20058232 details
MITFHINT1BioGRID22647378 details
MITFAPPBioGRID21832049 details
MITFFBXO7BioGRID27503909 details
MITFYWHAZMINT16822840 details
MITFTFEBBioGRID, HPRD, IntAct26496610 28514442 9806910 details
MITFTFE3BioGRID, HPRD, IntAct11818452 11930005 28514442 details
MITFSUMO1BioGRID, DIP, HPRD10694430 16029420 22012259 details
MITFFOSBioGRID, HPRD9918847 details
MITFTFECBioGRID, HPRD11818452 details
MITFEPAS1BioGRID23275444 details
MITFEP300BioGRID, HPRD9660747 details
MITFUCHL1BioGRID28392346 details
MITFOTX2HPRD12663655 details
MITFMAPK1HPRD9440696 details
MITFMAPK14HPRD11792706 details
MITFRPS6KA1HPRD10673502 details
MITFCTNNB1HPRD15729346 details
MITFPAX3HPRD15729346 details
MITFGSK3BHPRD10587587 details
MITFKLHL20BioGRID, IntAct28514442 details
MITFRBM6BioGRID, IntAct28514442 details
MITFYWHABIntAct28514442 details
MITFYWHAGIntAct28514442 details
MITFYWHAHIntAct28514442 details
MITFXPO1BioGRID26673895 details
MITFH4C1BioGRID30804502 details
MITFCCL15IntAct33179750 details
MITFXCL1IntAct33179750 details
MITFELAVL1BioGRID19322201 details
MITFTRIM25BioGRID29117863 details
MITFVIRMABioGRID29507755 details