Entity Details

Primary name MMP9
Entity type gene
Source Source Link

Details

PrimaryID4318
RefseqGeneNG_011468
SymbolMMP9
Namematrix metallopeptidase 9
Chromosome20
Location20q13.12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1996-06-27
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsMMP9_HUMAN

GO terms

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GOName
GO:0001501 skeletal system development
GO:0001503 ossification
GO:0001934 positive regulation of protein phosphorylation
GO:0004175 endopeptidase activity
GO:0004222 metalloendopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005518 collagen binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006508 proteolysis
GO:0007566 embryo implantation
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0019221 cytokine-mediated signaling pathway
GO:0022617 extracellular matrix disassembly
GO:0030198 extracellular matrix organization
GO:0030225 macrophage differentiation
GO:0030335 positive regulation of cell migration
GO:0030574 collagen catabolic process
GO:0034614 cellular response to reactive oxygen species
GO:0035987 endodermal cell differentiation
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043312 neutrophil degranulation
GO:0043388 positive regulation of DNA binding
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
GO:0048013 ephrin receptor signaling pathway
GO:0050900 leukocyte migration
GO:0051549 positive regulation of keratinocyte migration
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0071276 cellular response to cadmium ion
GO:0071492 cellular response to UV-A
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0150077 regulation of neuroinflammatory response
GO:1900122 positive regulation of receptor binding
GO:1904645 response to amyloid-beta
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:1904724 tertiary granule lumen
GO:1904813 ficolin-1-rich granule lumen
GO:2000697 negative regulation of epithelial cell differentiation involved in kidney development
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway
GO:2001258 negative regulation of cation channel activity
GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Diseases

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Interactions

57 interactions

InteractorPartnerSourcesPublicationsLink
MMP9ELNMINT20345904 details
MMP9SCUBE3I2D21441952 details
MMP9MEP1AMINT23123160 details
MMP9MEP1BMINT23123160 details
MMP9TGFB1BioGRID, IntAct10652271 25241761 details
MMP9MMP9DIP, HPRD, MINT12051944 17937912 18077379 23601700 details
MMP9VCANMINT23601700 details
MMP9SRGNMINT23601700 details
MMP9TIMP1BioGRID, IntAct24330623 28514442 details
MMP9CXCL5BioGRID, HPRD10095777 12950257 details
MMP9CXCL6BioGRID12950257 details
MMP9THBS1BioGRID, HPRD10900205 11606713 details
MMP9THBS2BioGRID, HPRD10900205 details
MMP9TGFBIBioGRID23019342 details
MMP9FN1BioGRID, HPRD, IntAct11134254 28514442 details
MMP9COL4A2BioGRID, HPRD, IntAct28514442 9878537 details
MMP9COL4A1BioGRID, HPRD, IntAct28514442 9878537 details
MMP9LCN2DIP, HPRD10339412 1281792 18077379 details
MMP9CLUBioGRID26716898 details
MMP9CTSBBioGRID26208400 details
MMP9HAPLN1HPRD7694569 details
MMP9COL4A3HPRD9878537 details
MMP9COL4A4HPRD9878537 details
MMP9COL1A1HPRD9878537 details
MMP9COL1A2HPRD9878537 details
MMP9CXCL8HPRD11023497 details
MMP9CXCL1HPRD11023497 details
MMP9PLGHPRD9360944 details
MMP9MMP7HPRD7896811 details
MMP9TIMP3HPRD11827795 details
MMP9COL4A5HPRD9878537 details
MMP9COL4A6HPRD9878537 details
MMP9BTCHPRD10706134 details
MMP9KISS1HPRD12879005 details
MMP9RECKHPRD9789069 details
MMP9MMP26HPRD12586837 details
MMP9TFPIHPRD10859319 details
MMP9PRSS2HPRD9261109 9578462 details
MMP9MMP10HPRD9578462 details
MMP9EPHB2HPRD18713744 details
MMP9AREGHPRD10389762 details
MMP9CD44HPRD10652271 17912438 details
MMP9ITGA5BioGRID, IntAct12724312 details
MMP9COL12A1BioGRID, IntAct28514442 details
MMP9SCARA3BioGRID, IntAct28514442 details
MMP9COL14A1BioGRID, IntAct28514442 details
MMP9COL18A1BioGRID, IntAct28514442 details
MMP9COL5A1BioGRID, IntAct28514442 details
MMP9COL6A2BioGRID, IntAct28514442 details
MMP9COL6A1BioGRID, IntAct28514442 details
MMP9COL2A1BioGRID, IntAct28514442 details
MMP9BIRC3BioGRID30948266 details
MMP9FBXW8BioGRID31343991 details
MMP9ERGIntAct20478527 details
MMP9RELAIntAct24413684 details
MMP9JUNIntAct22348975 25040843 details
MMP9MAFBIntAct24472656 details