Entity Details

Primary name NPPA
Entity type gene
Source Source Link

Details

PrimaryID4878
RefseqGeneNG_012926
SymbolNPPA
Namenatriuretic peptide A
Chromosome1
Location1p36.22
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsANF_HUMAN

GO terms

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GOName
GO:0003085 negative regulation of systemic arterial blood pressure
GO:0003161 cardiac conduction system development
GO:0003180 aortic valve morphogenesis
GO:0005102 signaling receptor binding
GO:0005179 hormone activity
GO:0005184 neuropeptide hormone activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006182 cGMP biosynthetic process
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006457 protein folding
GO:0007168 receptor guanylyl cyclase signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007565 female pregnancy
GO:0008217 regulation of blood pressure
GO:0010460 positive regulation of heart rate
GO:0019934 cGMP-mediated signaling
GO:0032991 protein-containing complex
GO:0035994 response to muscle stretch
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0042311 vasodilation
GO:0042995 cell projection
GO:0043204 perikaryon
GO:0043508 negative regulation of JUN kinase activity
GO:0051427 hormone receptor binding
GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization
GO:0060452 positive regulation of cardiac muscle contraction
GO:0062023 collagen-containing extracellular matrix
GO:0071855 neuropeptide receptor binding
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1901841 regulation of high voltage-gated calcium channel activity
GO:1902261 positive regulation of delayed rectifier potassium channel activity
GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
GO:1903766 positive regulation of potassium ion export across plasma membrane
GO:1903779 regulation of cardiac conduction
GO:1990000 amyloid fibril formation

Diseases

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Interactions

47 interactions

InteractorPartnerSourcesPublicationsLink
NPPAUBQLN4BioGRID, HPRD, IntAct16713569 details
NPPAMAGEA12BioGRID, IntAct25416956 32296183 details
NPPAUBQLN1BioGRID, IntAct25416956 details
NPPAHSF2BPBioGRID, IntAct32296183 details
NPPAUBQLN2BioGRID, IntAct32296183 details
NPPANPR3BioGRID, HPRD1309330 1660465 1672777 16870210 2169733 details
NPPANPR2BioGRID1309330 1660465 1672777 details
NPPAEPB41BioGRID12542678 details
NPPAHNF4ABioGRID, HPRD15604093 details
NPPAESR1BioGRID, HPRD15604093 details
NPPANR5A2BioGRID, HPRD15604093 details
NPPANPR1BioGRID, HPRD12547834 1660465 details
NPPAMMEBioGRID, HPRD2531377 2972276 9232196 details
NPPACST6BioGRID, IntAct28514442 details
NPPACPA4BioGRID, IntAct28514442 details
NPPASMYD2BioGRID, IntAct28514442 details
NPPAPDFBioGRID, IntAct28514442 details
NPPACAPNS2BioGRID, IntAct28514442 details
NPPAPOF1BBioGRID, IntAct28514442 details
NPPANUDT8BioGRID, IntAct28514442 details
NPPASDR9C7BioGRID, IntAct28514442 details
NPPAGDPD3BioGRID, IntAct28514442 details
NPPANDUFAF7BioGRID, IntAct28514442 details
NPPAPM20D1BioGRID, IntAct28514442 details
NPPAOBSCNBioGRID, IntAct28514442 details
NPPANDUFAF5BioGRID, IntAct28514442 details
NPPAECM1BioGRID, IntAct28514442 details
NPPAPMVKBioGRID, IntAct28514442 details
NPPAPMPCABioGRID, IntAct28514442 details
NPPALCN2BioGRID, IntAct28514442 details
NPPAMETAP1BioGRID, IntAct28514442 details
NPPAACADVLBioGRID, IntAct28514442 details
NPPASERPINB4BioGRID, IntAct28514442 details
NPPAME1BioGRID, IntAct28514442 details
NPPASERPINB3BioGRID, IntAct28514442 details
NPPATGM1BioGRID, IntAct28514442 details
NPPAACP3BioGRID, IntAct28514442 details
NPPAJUPBioGRID, IntAct28514442 details
NPPAIVLBioGRID, IntAct28514442 details
NPPAS100A9BioGRID, IntAct28514442 details
NPPAARG1BioGRID, IntAct28514442 details
NPPAPMPCBBioGRID, IntAct28514442 details
NPPAALOX12BBioGRID, IntAct28514442 details
NPPACTSVBioGRID, IntAct28514442 details
NPPAALOX15BBioGRID, IntAct28514442 details
NPPAIMPA2BioGRID, IntAct28514442 details
NPPAA2ML1BioGRID, IntAct28514442 details