Entity Details

Primary name NTRK3
Entity type gene
Source Source Link

Details

PrimaryID4916
RefseqGeneNG_029619
SymbolNTRK3
Nameneurotrophic receptor tyrosine kinase 3
Chromosome15
Location15q25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-21
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsNTRK3_HUMAN

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001933 negative regulation of protein phosphorylation
GO:0001934 positive regulation of protein phosphorylation
GO:0002039 p53 binding
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005030 neurotrophin receptor activity
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007399 nervous system development
GO:0007507 heart development
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010863 positive regulation of phospholipase C activity
GO:0010976 positive regulation of neuron projection development
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0030154 cell differentiation
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0032148 activation of protein kinase B activity
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0033674 positive regulation of kinase activity
GO:0043121 neurotrophin binding
GO:0043235 receptor complex
GO:0043410 positive regulation of MAPK cascade
GO:0050927 positive regulation of positive chemotaxis
GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway
GO:0051896 regulation of protein kinase B signaling
GO:0090630 activation of GTPase activity
GO:1990090 cellular response to nerve growth factor stimulus
GO:2000251 positive regulation of actin cytoskeleton reorganization

Diseases

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Interactions

63 interactions

InteractorPartnerSourcesPublicationsLink
NTRK3PTPN1BioGRID, HPRD, MINT12237455 details
NTRK3IRAK3BioGRID, IntAct21988832 details
NTRK3SORT1bhf-ucl, BioGRID21102451 details
NTRK3HTR2ADIP, HPRD16537434 details
NTRK3DOK6BioGRID, IntAct20565848 details
NTRK3NTF3BioGRID, HPRD8621424 9488719 9973222 details
NTRK3FRS2BioGRID10092678 details
NTRK3SHC1BioGRID, HPRD10092678 7657612 details
NTRK3PLCG1BioGRID, HPRD10092678 7657612 details
NTRK3APPBioGRID21832049 details
NTRK3ERBB2BioGRID30898150 details
NTRK3NELFBBioGRID24034695 details
NTRK3HEY1BioGRID24034695 details
NTRK3WDR13BioGRID24034695 details
NTRK3KPNA4BioGRID24034695 details
NTRK3NSD1BioGRID24034695 details
NTRK3BEX3HPRD10764727 details
NTRK3DOK5HPRD16647839 details
NTRK3SHC2HPRD12006576 details
NTRK3HSP90AB1IntAct22939624 details
NTRK3PTPRSBioGRID, IntAct25624497 28514442 details
NTRK3SQSTM1BioGRID, HPRD12471037 details
NTRK3HSP90AA1BioGRID22939624 details
NTRK3TNK2BioGRID23598414 details
NTRK3NDFIP1BioGRID29911254 details
NTRK3MAPK1HPRD11205744 9973222 details
NTRK3IRAK1HPRD12034707 details
NTRK3DYNLL1HPRD11157096 details
NTRK3MAPK3HPRD11205744 details
NTRK3KIDINS220HPRD15167895 details
NTRK3JUNHPRD9973222 details
NTRK3RASGRF1HPRD15513915 details
NTRK3NGFRHPRD9927421 details
NTRK3PKMIntAct24606918 details
NTRK3TBC1D24BioGRID, IntAct28514442 details
NTRK3SH3BP4BioGRID, IntAct28514442 details
NTRK3PAG1BioGRID, IntAct28514442 details
NTRK3INTS7BioGRID, IntAct28514442 details
NTRK3C1GALT1BioGRID, IntAct28514442 details
NTRK3GNB4BioGRID, IntAct28514442 details
NTRK3EHD4BioGRID, IntAct28514442 details
NTRK3MYADMBioGRID, IntAct28514442 details
NTRK3PTCD2BioGRID, IntAct28514442 details
NTRK3SLC39A11BioGRID, IntAct28514442 details
NTRK3RPTORBioGRID, IntAct28514442 details
NTRK3TMEM192BioGRID, IntAct28514442 details
NTRK3C6orf120BioGRID, IntAct28514442 details
NTRK3DENND4ABioGRID, IntAct28514442 details
NTRK3ACAD10BioGRID, IntAct28514442 details
NTRK3HEATR6BioGRID, IntAct28514442 details
NTRK3EFR3ABioGRID, IntAct28514442 details
NTRK3GNB2BioGRID, IntAct28514442 details
NTRK3CXCR4BioGRID, IntAct28514442 details
NTRK3MTORBioGRID, IntAct28514442 details
NTRK3ATP7BBioGRID, IntAct28514442 details
NTRK3EPHA2BioGRID, IntAct28514442 details
NTRK3TMEM11BioGRID, IntAct28514442 details
NTRK3LGALS1BioGRID, IntAct28514442 details
NTRK3HRASBioGRID, IntAct28514442 details
NTRK3PRORPBioGRID, IntAct28514442 details
NTRK3FAM171A2BioGRID, IntAct28514442 details
NTRK3NTRK1BioGRID25921289 details
NTRK3DDX58BioGRID32513696 details