Entity Details

Primary name ASIC2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ16515
EntryNameASIC2_HUMAN
FullNameAcid-sensing ion channel 2
TaxID9606
Evidenceevidence at protein level
Length512
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesASIC2

GO terms

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GOName
GO:0003026 regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007268 chemical synaptic transmission
GO:0007417 central nervous system development
GO:0007422 peripheral nervous system development
GO:0007602 phototransduction
GO:0007605 sensory perception of sound
GO:0010447 response to acidic pH
GO:0015280 ligand-gated sodium channel activity
GO:0019229 regulation of vasoconstriction
GO:0022839 ion gated channel activity
GO:0034220 ion transmembrane transport
GO:0034765 regulation of ion transmembrane transport
GO:0035418 protein localization to synapse
GO:0035725 sodium ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0043025 neuronal cell body
GO:0043066 negative regulation of apoptotic process
GO:0043197 dendritic spine
GO:0050915 sensory perception of sour taste
GO:0050974 detection of mechanical stimulus involved in sensory perception
GO:0051965 positive regulation of synapse assembly
GO:0098662 inorganic cation transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001873 Epithelial sodium channelFamilyFamily
IPR004724 Epithelial sodium channel, chordatesFamilyFamily
IPR020903 Epithelial sodium channel, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00594 AmilorideDrugbanksmall molecule

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
ASIC2_HUMANPICK1_HUMANHPRD, UniProt11739374 11802773 details
ASIC2_HUMANASIC1_HUMANBioGRID, HPRD, IntAct28514442 9360943 details
ASIC2_HUMANASIC3_HUMANBioGRID, HPRD10842183 details
ASIC2_HUMANSTOM_HUMANBioGRID, HPRD15471860 details