Entity Details

Primary name IF16_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ16666
EntryNameIF16_HUMAN
FullNameGamma-interferon-inducible protein 16
TaxID9606
Evidenceevidence at protein level
Length785
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesIFI16

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001819 positive regulation of cytokine production
GO:0002218 activation of innate immune response
GO:0003690 double-stranded DNA binding
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0006914 autophagy
GO:0006954 inflammatory response
GO:0008134 transcription factor binding
GO:0010506 regulation of autophagy
GO:0016020 membrane
GO:0016607 nuclear speck
GO:0030099 myeloid cell differentiation
GO:0030224 monocyte differentiation
GO:0032481 positive regulation of type I interferon production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0035458 cellular response to interferon-beta
GO:0040029 regulation of gene expression, epigenetic
GO:0042149 cellular response to glucose starvation
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042802 identical protein binding
GO:0043392 negative regulation of DNA binding
GO:0045071 negative regulation of viral genome replication
GO:0045087 innate immune response
GO:0045824 negative regulation of innate immune response
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051607 defense response to virus
GO:0071479 cellular response to ionizing radiation
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0097202 activation of cysteine-type endopeptidase activity
GO:2000117 negative regulation of cysteine-type endopeptidase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR004020 DAPIN domainDomainDomain
IPR004021 HIN-200/IF120xDomainDomain
IPR040205 HIN-200 familyFamilyFamily

Diseases

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