Entity Details

Primary name PSENEN
Entity type gene
Source Source Link

Details

PrimaryID55851
RefseqGeneNG_027934
SymbolPSENEN
Namepresenilin enhancer, gamma-secretase subunit
Chromosome19
Location19q13.12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-07-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPEN2_HUMAN

GO terms

Show/Hide Table
GOName
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006509 membrane protein ectodomain proteolysis
GO:0007220 Notch receptor processing
GO:0010008 endosome membrane
GO:0010950 positive regulation of endopeptidase activity
GO:0016021 integral component of membrane
GO:0016485 protein processing
GO:0019899 enzyme binding
GO:0031293 membrane protein intracellular domain proteolysis
GO:0032580 Golgi cisterna membrane
GO:0034205 amyloid-beta formation
GO:0035333 Notch receptor processing, ligand-dependent
GO:0042982 amyloid precursor protein metabolic process
GO:0042987 amyloid precursor protein catabolic process
GO:0043065 positive regulation of apoptotic process
GO:0043085 positive regulation of catalytic activity
GO:0048013 ephrin receptor signaling pathway
GO:0061133 endopeptidase activator activity
GO:0070765 gamma-secretase complex
GO:1990000 amyloid fibril formation

Diseases

Show/Hide Table