Entity Details

Primary name RAC2
Entity type gene
Source Source Link

Details

PrimaryID5880
RefseqGeneNG_007288
SymbolRAC2
NameRac family small GTPase 2
Chromosome22
Location22q13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-25
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsRAC2_HUMAN

GO terms

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GOName
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005635 nuclear envelope
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0005938 cell cortex
GO:0007015 actin filament organization
GO:0007163 establishment or maintenance of cell polarity
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0008045 motor neuron axon guidance
GO:0008284 positive regulation of cell population proliferation
GO:0008360 regulation of cell shape
GO:0010310 regulation of hydrogen peroxide metabolic process
GO:0010592 positive regulation of lamellipodium assembly
GO:0010810 regulation of cell-substrate adhesion
GO:0016601 Rac protein signal transduction
GO:0019887 protein kinase regulator activity
GO:0019901 protein kinase binding
GO:0030027 lamellipodium
GO:0030031 cell projection assembly
GO:0030670 phagocytic vesicle membrane
GO:0030865 cortical cytoskeleton organization
GO:0031410 cytoplasmic vesicle
GO:0032956 regulation of actin cytoskeleton organization
GO:0042129 regulation of T cell proliferation
GO:0042995 cell projection
GO:0043231 intracellular membrane-bounded organelle
GO:0043304 regulation of mast cell degranulation
GO:0043652 engulfment of apoptotic cell
GO:0045453 bone resorption
GO:0045454 cell redox homeostasis
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0051897 positive regulation of protein kinase B signaling
GO:0060263 regulation of respiratory burst
GO:0060753 regulation of mast cell chemotaxis
GO:0070062 extracellular exosome
GO:0071593 lymphocyte aggregation
GO:0090023 positive regulation of neutrophil chemotaxis
GO:1902622 regulation of neutrophil migration
GO:1903955 positive regulation of protein targeting to mitochondrion

Diseases

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Interactions

45 interactions

InteractorPartnerSourcesPublicationsLink
RAC2ARHGDIBBioGRID, HPRD, MINT10655614 details
RAC2NCF2BioGRID, HPRD, MINT11090627 9624165 9642115 details
RAC2ADAM22BioGRID, IntAct21988832 details
RAC2AFG3L2BioGRID, MINT21900206 details
RAC2CHGBBioGRID, MINT21900206 details
RAC2XIAPMINT22117219 details
RAC2HDAC7BioGRID, IntAct32296183 details
RAC2ARFIP2BioGRID, HPRD, IntAct11346801 32296183 details
RAC2PLD2DIP22106281 details
RAC2DOCK2BioGRID, DIP, HPRD10559471 14737186 details
RAC2CUL1BioGRID, HPRD11445862 details
RAC2DEF6BioGRID, HPRD15023524 details
RAC2ACTBBioGRID, HPRD11027608 details
RAC2ICMTBioGRID, HPRD9614111 details
RAC2NOS2BioGRID, HPRD11457725 details
RAC2PAK2BioGRID12176041 details
RAC2ARHGDIABioGRID, HPRD11368848 11513578 9490022 details
RAC2AGAP2BioGRID22453919 details
RAC2NOXA1HPRD12716910 details
RAC2CYBBInnateDB22366891 details
RAC2WASmbinfo14521508 details
RAC2PAK1mbinfo14521508 details
RAC2RAC2mbinfo9748241 details
RAC2TNFAIP8L2DIP22949657 details
RAC2ITGA4BioGRID22623428 details
RAC2U2AF2BioGRID26641092 details
RAC2GDI1HPRD9490022 details
RAC2CDC42HPRD9748241 details
RAC2SMAD1HPRD15761153 details
RAC2SMAD4HPRD15761153 details
RAC2RTKNHPRD12516569 details
RAC2VCAM1BioGRID, IntAct19738201 22623428 details
RAC2HDAC10BioGRID, IntAct23752268 details
RAC2ELMO2BioGRID, IntAct28514442 details
RAC2DOCK1BioGRID, IntAct28514442 details
RAC2RAC3BioGRID, IntAct28514442 details
RAC2RAP1GDS1BioGRID, IntAct28514442 details
RAC2CD81BioGRID23463506 details
RAC2FBXO6BioGRID22268729 details
RAC2CFTRBioGRID26618866 details
RAC2PLEKHA2BioGRID19786618 details
RAC2NR2C2BioGRID30463901 details
RAC2FANCD2BioGRID31180492 details
RAC2NHLRC2BioGRID30397336 details
RAC2KIF14BioGRID31586073 details