Entity Details

Primary name CBS
Entity type gene
Source Source Link

Details

PrimaryID875
RefseqGeneNG_008938
SymbolCBS
Namecystathionine beta-synthase
Chromosome21
Location21q22.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1988-07-20
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsCBSL_HUMAN
CBS_HUMAN

GO terms

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GOName
GO:0004122 cystathionine beta-synthase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006535 cysteine biosynthetic process from serine
GO:0006563 L-serine metabolic process
GO:0006565 L-serine catabolic process
GO:0019343 cysteine biosynthetic process via cystathionine
GO:0019344 cysteine biosynthetic process
GO:0019346 transsulfuration
GO:0019448 L-cysteine catabolic process
GO:0019825 oxygen binding
GO:0019899 enzyme binding
GO:0020037 heme binding
GO:0030170 pyridoxal phosphate binding
GO:0031625 ubiquitin protein ligase binding
GO:0042262 DNA protection
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043418 homocysteine catabolic process
GO:0046872 metal ion binding
GO:0050421 nitrite reductase (NO-forming) activity
GO:0050667 homocysteine metabolic process
GO:0070025 carbon monoxide binding
GO:0070026 nitric oxide binding
GO:0070814 hydrogen sulfide biosynthetic process
GO:0072341 modified amino acid binding
GO:1904047 S-adenosyl-L-methionine binding

Diseases

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Interactions

113 interactions

InteractorPartnerSourcesPublicationsLink
CBSVTA1BioGRID, HPRD, IntAct16189514 31515488 details
CBSFXR2BioGRID, HPRD, IntAct, MINT16189514 21653829 31515488 details
CBSHID1BioGRID, HPRD, IntAct16189514 31515488 details
CBSCBSLIntAct, MINT16189514 19447967 21900206 25416956 25502805 31515488 details
CBSCBSBioGRID, HPRD, IntAct, MINT11173483 11483494 12173932 16189514 19447967 21516116 21900206 25416956 25502805 31515488 details
CBSCERT1BioGRID, IntAct19447967 details
CBSUGP2BioGRID, IntAct21988832 details
CBSDAXXBioGRID, IntAct21988832 details
CBSPRKAR1ABioGRID, MINT21900206 details
CBSZDHHC17BioGRID, IntAct24705354 details
CBSPSMA1BioGRID, IntAct25416956 31515488 details
CBSPRKAG1BioGRID, IntAct25416956 details
CBSUBASH3ABioGRID, IntAct25416956 31515488 details
CBSEHHADHBioGRID, IntAct25416956 31515488 details
CBSPIN1BioGRID, IntAct25416956 31515488 details
CBSNTAQ1BioGRID, IntAct27107012 details
CBSPIAS2BioGRID, IntAct32296183 details
CBSZMYM5BioGRID, IntAct32296183 details
CBSGALIntAct32814053 details
CBSKAT5IntAct32814053 details
CBSCYTH1IntAct32814053 details
CBSFKBP6IntAct32814053 details
CBSPRKACAIntAct32814053 details
CBSFYNIntAct32814053 details
CBSCTNNB1IntAct32814053 details
CBSCAMK2AIntAct32814053 details
CBSHTTHPRD, IntAct10434301 32814053 9466992 details
CBSHGSBioGRID19019082 details
CBSPIAS1BioGRID17087506 details
CBSPIAS3BioGRID17087506 details
CBSUBE2IBioGRID17087506 25416956 32296183 details
CBSRANBP9BioGRID17087506 details
CBSCBX4BioGRID17087506 details
CBSPA2G4BioGRID, IntAct27173435 unassigned1312 details
CBSNEK7BioGRID, IntAct27173435 unassigned1312 details
CBSUBE2NBioGRID, IntAct27173435 unassigned1312 details
CBSTRAP1BioGRID, IntAct27173435 unassigned1312 details
CBSFXR1MINT21653829 details
CBSGABARAPIntAct20562859 details
CBSOTUB1BioGRID, IntAct26752685 details
CBSHSPA8IntAct25910212 details
CBSHSP90AB1IntAct25910212 details
CBSTPM1BioGRID, IntAct30021884 details
CBSEIF3BBioGRID, IntAct30021884 details
CBSTPT1MINT27607350 details
CBSLRRK2IntAct31046837 details
CBSARHGAP29BioGRID, IntAct32203420 details
CBSPREX1BioGRID, IntAct32203420 details
CBSARHGAP11BBioGRID, IntAct32203420 details
CBSZDHHC5UniProt31402609 details
CBSUBCBioGRID16196087 details
CBSCDK2BioGRID21319273 details
CBSGPSM1BioGRID23718855 details
CBSGON7BioGRID22863883 details
CBSDBNLBioGRID22863883 details
CBSDERABioGRID22863883 details
CBSNPLOC4BioGRID22863883 details
CBSNUCB1BioGRID22863883 details
CBSPKMBioGRID22863883 details
CBSPLIN3BioGRID22863883 details
CBSERO1ABioGRID22863883 details
CBSGOPCBioGRID22863883 details
CBSGPN1BioGRID22863883 details
CBSHSF1BioGRID22863883 details
CBSIPO4BioGRID22863883 details
CBSIREB2BioGRID22863883 details
CBSLRSAM1BioGRID22863883 details
CBSPARP6BioGRID22863883 details
CBSPDLIM5BioGRID22863883 details
CBSRAD23BBioGRID22863883 details
CBSSRP14BioGRID22863883 details
CBSUBA2BioGRID22863883 details
CBSUBA5BioGRID22863883 details
CBSAP1B1BioGRID26344197 details
CBSCARS1BioGRID26344197 details
CBSABATBioGRID26344197 details
CBSASNSBioGRID26344197 details
CBSEEF1A1BioGRID26344197 details
CBSENOPH1BioGRID26344197 details
CBSOATBioGRID26344197 details
CBSRSU1BioGRID26344197 details
CBSRTF2BioGRID26344197 details
CBSSKIV2LBioGRID26344197 details
CBSVBP1BioGRID26344197 details
CBSCTHBioGRID26344197 details
CBSHSPE1BioGRID26344197 details
CBSIARS1BioGRID26344197 details
CBSNMD3BioGRID26344197 details
CBSQARS1BioGRID26344197 details
CBSSEC24BBioGRID26344197 details
CBSSEC31ABioGRID26344197 details
CBSUBE3BBioGRID26344197 details
CBSNTRK1BioGRID25921289 details
CBSNF2BioGRID26549023 details
CBSPTPRRBioGRID27432908 details
CBSEGLN3BioGRID26972000 details
CBSEFTUD2BioGRID28515276 details
CBSAAR2BioGRID28515276 details
CBSPIH1D1BioGRID28515276 details
CBSSNAI1BioGRID29331416 details
CBSRECQL4BioGRID29229926 details
CBSBIRC3BioGRID30948266 details
CBSSTAU1BioGRID30948266 details
CBSWWP2BioGRID31048545 details
CBSCTBP2BioGRID30585266 details
CBSTRIM28BioGRID29955894 details
CBSPLEKHA4BioGRID31091453 details
CBSKIF23BioGRID31586073 details
CBSARHGAP26BioGRID32203420 details
CBSARHGAP32BioGRID32203420 details
CBSARHGAP35BioGRID32203420 details
CBSCOPS5BioGRID31950832 details
CBSKDF1BioGRID32239614 details