Entity Details

Primary name BCL10
Entity type gene
Source Source Link

Details

PrimaryID8915
RefseqGeneNG_012216
SymbolBCL10
NameBCL10 immune signaling adaptor
Chromosome1
Location1p22.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-01-08
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsBCL10_HUMAN

GO terms

Show/Hide Table
GOName
GO:0001772 immunological synapse
GO:0001783 B cell apoptotic process
GO:0001843 neural tube closure
GO:0002020 protease binding
GO:0002096 polkadots
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002224 toll-like receptor signaling pathway
GO:0002250 adaptive immune response
GO:0002906 negative regulation of mature B cell apoptotic process
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005829 cytosol
GO:0005881 cytoplasmic microtubule
GO:0006968 cellular defense response
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0008219 cell death
GO:0009620 response to fungus
GO:0016064 immunoglobulin mediated immune response
GO:0016567 protein ubiquitination
GO:0019899 enzyme binding
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0031398 positive regulation of protein ubiquitination
GO:0031625 ubiquitin protein ligase binding
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0032094 response to food
GO:0032449 CBM complex
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032761 positive regulation of lymphotoxin A production
GO:0032765 positive regulation of mast cell cytokine production
GO:0032991 protein-containing complex
GO:0033674 positive regulation of kinase activity
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042327 positive regulation of phosphorylation
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043422 protein kinase B binding
GO:0043621 protein self-association
GO:0044877 protein-containing complex binding
GO:0045087 innate immune response
GO:0045121 membrane raft
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048471 perinuclear region of cytoplasm
GO:0050700 CARD domain binding
GO:0050852 T cell receptor signaling pathway
GO:0050856 regulation of T cell receptor signaling pathway
GO:0050870 positive regulation of T cell activation
GO:0051059 NF-kappaB binding
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0070231 T cell apoptotic process
GO:0071222 cellular response to lipopolysaccharide
GO:0071260 cellular response to mechanical stimulus
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway

Diseases

Show/Hide Table

Interactions

89 interactions

InteractorPartnerSourcesPublicationsLink
BCL10CARD19BioGRID, HPRD, MINT15637807 details
BCL10AKT1BioGRID, HPRD, IntAct, MINT16280327 24412244 24462114 details
BCL10IKBKGBioGRID, DIP, HPRD, IntAct, MINT11113112 14695475 15184390 17363905 18287044 19897484 23690623 27070702 27777308 details
BCL10CARD11BioGRID, DIP, HPRD, IntAct, MINT11278692 11356195 16356855 17948050 18625728 18806265 19118383 19444310 19815501 21157432 21513986 22528498 23690623 24074955 25548215 27777308 30279415 details
BCL10MALT1BioGRID, DIP, HPRD, InnateDB, IntAct, MINT11090634 11262391 14695475 17189706 17948050 18806265 19118383 19279678 19444310 20551178 21157432 21513986 22267217 22528498 22658522 23690623 24130731 25548215 25569716 25748427 27070702 27071417 27113748 27777308 29953499 30279415 31961340 33329596 details
BCL10CDK9BioGRID, IntAct21988832 details
BCL10IL15RABioGRID, IntAct21988832 details
BCL10SRSF1BioGRID, IntAct21988832 details
BCL10SLC20A1BioGRID, IntAct21988832 details
BCL10SLC9A3R1BioGRID, IntAct21988832 details
BCL10PRRG4BioGRID, IntAct21988832 details
BCL10USHBP1BioGRID, IntAct21988832 details
BCL10CARD9BioGRID, HPRD, InnateDB, IntAct11053425 22267217 25416956 28765954 details
BCL10ANP32BBioGRID, MINT24412244 details
BCL10BAATBioGRID, MINT24412244 details
BCL10FBP1BioGRID, MINT24412244 details
BCL10TRMOBioGRID, MINT24412244 details
BCL10CDC14BBioGRID, MINT24412244 details
BCL10HEMGNBioGRID, MINT24412244 details
BCL10CCDC180BioGRID, MINT24412244 details
BCL10NANSBioGRID, MINT24412244 details
BCL10RASA1BioGRID, MINT24412244 details
BCL10TGFB1BioGRID, MINT24412244 details
BCL10TRAF2BioGRID, HPRD, IntAct10753917 11466612 25416956 25910212 32296183 details
BCL10BCL10BioGRID, HPIDb, HPRD, IntAct10187771 15125833 16775419 21896478 24074955 25416956 29382759 32296183 details
BCL10COG6BioGRID, IntAct27107012 32296183 details
BCL10IKBKBBioGRID, DIP11113112 14695475 17213322 19118383 details
BCL10TNFRSF10ABioGRID, HPRD10400625 details
BCL10TNFRSF1ABioGRID10400625 details
BCL10CARD10BioGRID, HPRD11259443 11387339 15184390 details
BCL10CARD14BioGRID, HPRD11278692 27071417 details
BCL10BIRC3BioGRID10753917 11466612 16395405 16775419 details
BCL10IRAK1BioGRID16831874 details
BCL10MIB2BioGRID21896478 details
BCL10CHUKBioGRID, HPRD11113112 14695475 22547678 details
BCL10ATMBioGRID24732096 details
BCL10UBE2V2BioGRID, HPRD14695475 details
BCL10UBE2NBioGRID, HPRD14695475 details
BCL10RNF181BioGRID26711259 details
BCL10OTULINBioGRID27777308 details
BCL10BCL3BioGRID, IntAct16280327 details
BCL10PRKCQBioGRID, MINT17363905 20164171 details
BCL10COPS5MINT19444310 details
BCL10PRKCZIntAct25011391 details
BCL10CSNK1A1BioGRID, DIP19118383 20551178 25088585 details
BCL10TRADDBioGRID, HPRD10400625 details
BCL10NLRC4BioGRID, HPRD11472070 details
BCL10BIRC2BioGRID10753917 16775419 details
BCL10XIAPBioGRID16775419 details
BCL10NFKBIABioGRID20551178 details
BCL10FYB1BioGRID20164171 details
BCL10CAMK2GBioGRID21513986 details
BCL10TRAF6BioGRID16920630 details
BCL10DPP4BioGRID17287217 details
BCL10MAPK9BioGRID17189706 details
BCL10MAP3K7BioGRID, HPRD16186825 17189706 details
BCL10MAP2K7BioGRID17189706 details
BCL10USP9XBioGRID23690623 details
BCL10RNF8BioGRID24732096 details
BCL10RNF168BioGRID24732096 details
BCL10PPP2R1ABioGRID21157432 details
BCL10PPP2CABioGRID21157432 details
BCL10SQSTM1BioGRID22658522 details
BCL10MAP1LC3ABioGRID22658522 details
BCL10ATG5BioGRID22658522 details
BCL10RNF31BioGRID27777308 details
BCL10TMEM43BioGRID27991920 details
BCL10RBCK1BioGRID33329596 details
BCL10CASP9HPRD10187815 details
BCL10TLR4HPRD15213237 details
BCL10RIPK2HPRD14638696 details
BCL10SOCS3HPRD15213237 details
BCL10PELI2HPRD15213237 details
BCL10KRT33BBioGRID, IntAct17353931 details
BCL10H2BC5IntAct17353931 details
BCL10H2BC8IntAct17353931 details
BCL10H2BC7IntAct17353931 details
BCL10H2BC6IntAct17353931 details
BCL10H2BC10IntAct17353931 details
BCL10H2BC4BioGRID, IntAct17353931 details
BCL10CASP8InnateDB22267217 details
BCL10PYCARDInnateDB22267217 details
BCL10CEP43BioGRID, IntAct26638075 details
BCL10SHARPINIntAct27070702 details
BCL10BTRCBioGRID, DIP17213322 details
BCL10ENGBioGRID, UniProt31540324 details
BCL10XPO1BioGRID26673895 details
BCL10RELAIntAct16280327 details
BCL10ELAVL1BioGRID19322201 details