Entity Details

Primary name PLCZ1
Entity type gene
Source Source Link

Details

PrimaryID89869
RefseqGeneNG_052826
SymbolPLCZ1
Namephospholipase C zeta 1
Chromosome12
Location12p12.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-07-02
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPLCZ1_HUMAN

GO terms

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GOName
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0005509 calcium ion binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005634 nucleus
GO:0005829 cytosol
GO:0006816 calcium ion transport
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007275 multicellular organism development
GO:0007343 egg activation
GO:0010314 phosphatidylinositol-5-phosphate binding
GO:0016042 lipid catabolic process
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0043647 inositol phosphate metabolic process
GO:0048015 phosphatidylinositol-mediated signaling
GO:0048471 perinuclear region of cytoplasm
GO:0060470 positive regulation of cytosolic calcium ion concentration involved in egg activation
GO:0061827 sperm head

Diseases

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Interactions

10 interactions

InteractorPartnerSourcesPublicationsLink
PLCZ1CST6BioGRID, IntAct26186194 28514442 details
PLCZ1SERPINA12BioGRID, IntAct26186194 28514442 details
PLCZ1ECM1BioGRID, IntAct28514442 details
PLCZ1KLK7BioGRID, IntAct26186194 28514442 details
PLCZ1HALBioGRID, IntAct26186194 28514442 details
PLCZ1SEMG1BioGRID, IntAct26186194 28514442 details
PLCZ1NPM1BioGRID, IntAct30021884 details
PLCZ1ACTC1BioGRID, IntAct30021884 details
PLCZ1PRKCSHBioGRID, IntAct30021884 details
PLCZ1HBDBioGRID26186194 details