Entity Details

Primary name ARH_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5SW96
EntryNameARH_HUMAN
FullNameLow density lipoprotein receptor adapter protein 1
TaxID9606
Evidenceevidence at protein level
Length308
SequenceStatuscomplete
DateCreated2005-08-30
DateModified2021-06-02

Ontological Relatives

GenesLDLRAP1

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001784 phosphotyrosine residue binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005883 neurofilament
GO:0005886 plasma membrane
GO:0006898 receptor-mediated endocytosis
GO:0008203 cholesterol metabolic process
GO:0009898 cytoplasmic side of plasma membrane
GO:0009925 basal plasma membrane
GO:0030159 signaling receptor complex adaptor activity
GO:0030276 clathrin binding
GO:0030301 cholesterol transport
GO:0030424 axon
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0031623 receptor internalization
GO:0034383 low-density lipoprotein particle clearance
GO:0035591 signaling adaptor activity
GO:0035612 AP-2 adaptor complex binding
GO:0035615 clathrin adaptor activity
GO:0035650 AP-1 adaptor complex binding
GO:0042632 cholesterol homeostasis
GO:0042982 amyloid precursor protein metabolic process
GO:0043393 regulation of protein binding
GO:0048260 positive regulation of receptor-mediated endocytosis
GO:0050750 low-density lipoprotein particle receptor binding
GO:0055037 recycling endosome
GO:0061024 membrane organization
GO:0071345 cellular response to cytokine stimulus
GO:0090118 receptor-mediated endocytosis involved in cholesterol transport
GO:0090205 positive regulation of cholesterol metabolic process
GO:1903076 regulation of protein localization to plasma membrane
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:1905581 positive regulation of low-density lipoprotein particle clearance
GO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR006020 PTB/PI domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily

Diseases

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