Entity Details

Primary name STXB5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5T5C0
EntryNameSTXB5_HUMAN
FullNameSyntaxin-binding protein 5
TaxID9606
Evidenceevidence at protein level
Length1151
SequenceStatuscomplete
DateCreated2005-11-22
DateModified2021-06-02

Ontological Relatives

GenesSTXBP5

GO terms

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GOName
GO:0005096 GTPase activator activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005892 acetylcholine-gated channel complex
GO:0006887 exocytosis
GO:0008021 synaptic vesicle
GO:0010807 regulation of synaptic vesicle priming
GO:0015031 protein transport
GO:0017075 syntaxin-1 binding
GO:0017157 regulation of exocytosis
GO:0019905 syntaxin binding
GO:0031201 SNARE complex
GO:0031594 neuromuscular junction
GO:0045159 myosin II binding
GO:0045921 positive regulation of exocytosis
GO:0050708 regulation of protein secretion
GO:0098674 extrinsic component of neuronal dense core vesicle membrane
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098686 hippocampal mossy fiber to CA3 synapse
GO:0098888 extrinsic component of presynaptic membrane
GO:0099504 synaptic vesicle cycle
GO:0099523 presynaptic cytosol
GO:2000300 regulation of synaptic vesicle exocytosis

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cytoplasm
Cytoplasmic vesicle
Cytoplasmic vesicle membrane

Domains

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DomainNameCategoryType
IPR000664 Lethal(2) giant larvae proteinFamilyFamily
IPR001680 WD40 repeatRepeatRepeat
IPR013577 Lethal giant larvae homologue 2DomainDomain
IPR013905 Lethal giant larvae (Lgl)-like, C-terminal domainDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily
IPR042855 v-SNARE, coiled-coil homology domainDomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
STXB5_HUMANSTX1A_HUMANBioGRID, HPRD12832401 9620695 details
STXB5_HUMANSTX4_HUMANBioGRID, HPRD12832401 34079125 details
STXB5_HUMANSNP23_HUMANBioGRID, HPRD12832401 details