Interaction Details

Interaction: SHC1_HUMAN  -  EGFR_HUMAN
Standard Confidence level: 1
Cross-Checked Confidence level: 1
Primary sources: MINT, IntAct, I2D, DIP, BioGRID, HPRD
Number of publications: 49

Source Information

SourceInteractor AInteractor BQualityInteraction type(s)Detection method(s)ThroughputExpansionPublications
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19561direct interactionunspecified methodHigh-16273093
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19561direct interactiontwo hybridLow-25402006
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19561direct interactionprotein complementation assayHigh-24658140
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19561direct interactionpull downLow-8810340
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19561direct interactiontwo hybridLow-28065597
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19561direct interactionpull downLow-24430869
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19561direct interactionenzymatic studyLow-9388490
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19561direct interactionpull downLow-8610109
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19561direct interactionenzymatic studyLow-26551075
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19561direct interactionpull downLow-7542991
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19561direct interactionpull downLow-25187647
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19561direct interactionpull downHigh-22973453
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-16729043
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-9544989
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-9756944
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-9130710
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-11370743
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-11408594
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-10595738
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-10049786
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-10635327
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-8662998
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-23799367
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow and High-23956138
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-7506413
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-24658140
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-24189400
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-8810340
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-10766863
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-24430869
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-20473329
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-11196191
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-8665853
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-25187647
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-20067773
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-9020193
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19562physical associationaffinity chromatography technologyLow-30544639
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19563physical associationaffinity chromatography technologyHigh-19531499
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19563physical associationaffinity chromatography technologyHigh-18271526
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19563physical associationaffinity chromatography technologyHigh-24797263
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19563physical associationaffinity chromatography technologyHigh-24189400
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19563physical associationaffinity chromatography technologyHigh-25754235
BioGRIDentrez gene/locuslink:6464entrez gene/locuslink:19563physical associationaffinity chromatography technologyHigh-31959764
DIPuniprotkb:P29353uniprotkb:P005331direct interactionx-ray crystallography--26551075
DIPuniprotkb:P29353uniprotkb:P005331phosphorylation reactionprotein kinase assay--26551075
HPRD02780005792-in vivo; in vitro--12577067 16729043 7518560 8887653 9544989
I2Duniprotkb:P29353uniprotkb:P005332physical associationanti bait coimmunoprecipitation--20935677
I2Duniprotkb:P29353uniprotkb:P005333associationanti bait coimmunoprecipitation-spoke expansion21278788
IntActuniprotkb:P29353-7uniprotkb:P005331physical associationubiquitin reconstruction--24658140
IntActuniprotkb:P29353uniprotkb:P005331physical associationubiquitin reconstruction--31980649
IntActuniprotkb:P29353-7uniprotkb:P005332physical associationluminescence based mammalian interactome mapping--24658140
IntActuniprotkb:P29353-7uniprotkb:P005332physical associationanti tag coimmunoprecipitation--24658140
IntActuniprotkb:P29353uniprotkb:P005333associationanti bait coimmunoprecipitation-spoke expansion15657067
IntActuniprotkb:P29353uniprotkb:P005333associationtandem affinity purification-spoke expansion24189400
IntActuniprotkb:P29353uniprotkb:P005333associationanti bait coimmunoprecipitation-spoke expansion24189400
IntActuniprotkb:P29353uniprotkb:P005333associationanti tag coimmunoprecipitation-spoke expansion31585087
MINTuniprotkb:P29353uniprotkb:P005331direct interactionprotein array--16273093
MINTuniprotkb:P29353uniprotkb:P005331associationcompetition binding--8034616
MINTuniprotkb:P29353uniprotkb:P005331physical associationubiquitin reconstruction--28065597
MINTuniprotkb:P29353uniprotkb:P005332physical associationcoimmunoprecipitation--8662998
MINTuniprotkb:P29353uniprotkb:P005332physical associationpull down--16729043
MINTuniprotkb:P29353uniprotkb:P005332physical associationanti bait coimmunoprecipitation--9544989
MINTuniprotkb:P29353uniprotkb:P005332associationexperimental interaction detection--9544989
MINTuniprotkb:P29353uniprotkb:P005332associationcoimmunoprecipitation--7518560
MINTuniprotkb:P29353uniprotkb:P005332associationcoimmunoprecipitation--7542744
MINTuniprotkb:P29353uniprotkb:P005332associationcoimmunoprecipitation--8034616
MINTuniprotkb:P29353uniprotkb:P005332physical associationanti bait coimmunoprecipitation--23178716
MINTuniprotkb:P29353uniprotkb:P005332physical associationanti bait coimmunoprecipitation--23799367
MINTuniprotkb:P29353uniprotkb:P005333associationanti bait coimmunoprecipitation-spoke expansion23178716