Interaction Details

Interaction: SMAD3_HUMAN  -  SMAD4_HUMAN
Standard Confidence level: 1
Cross-Checked Confidence level: 1
Primary sources: MINT, IntAct, I2D, BioGRID, HPRD
Number of publications: 59

Source Information

SourceInteractor AInteractor BQualityInteraction type(s)Detection method(s)ThroughputExpansionPublications
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactionpull downLow-12732634
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactionpull downLow-22045334
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactionpull downLow-19135894
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactionpull downLow-17283070
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactionpull downLow-17591701
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactionpull downLow-15350224
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactionpull downLow-10092624
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactiontwo hybridLow-9111321
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactionpull downLow-9111321
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactionpull downLow-15467747
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactiontwo hybridHigh-15231748
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactiontwo hybridHigh-21988832
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactionpull downLow-24157709
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactionpull downLow-19917253
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactionprotein complementation assayLow-26555259
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactiontwo hybridHigh-25910212
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactiontwo hybridHigh-27107012
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactionfluorescent resonance energy transferHigh-29997244
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40891direct interactiontwo hybridHigh-29892012
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-15084259
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-12794086
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-12419246
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-9311995
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-10531362
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-9892009
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-11114293
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-20142324
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-12167862
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-20564330
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-19135894
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-10878024
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-10995777
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-12917407
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-21532621
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-22310290
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-19917253
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-19768112
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-18729074
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-15922743
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-15761153
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892associationx-ray crystallographyLow-15350224
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-15350224
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-10092624
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-12543979
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-19139564
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-23788427
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-24382352
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-11927552
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-15588252
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-24584437
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-25514493
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-26555259
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-28115363
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-27845895
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-28443643
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-18055455
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40892physical associationaffinity chromatography technologyLow-31591477
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40893physical associationaffinity chromatography technologyHigh-18729074
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40893physical associationaffinity chromatography technologyHigh-25609649
BioGRIDentrez gene/locuslink:4088entrez gene/locuslink:40893physical associationaffinity chromatography technologyHigh-27703004
HPRD04380029951-in vitro; two hybrid; in vivo--10995777 15231748 15350224 9311995
I2Duniprotkb:P84022uniprotkb:Q134852physical associationanti bait coimmunoprecipitation--21297662
I2Duniprotkb:P84022uniprotkb:Q134853associationanti bait coimmunoprecipitation-spoke expansion21532621
IntActuniprotkb:P84022uniprotkb:Q134851direct interactionx-ray crystallography--15350224
IntActuniprotkb:P84022uniprotkb:Q134851direct interactionpull down--19135894
IntActuniprotkb:P84022uniprotkb:Q134851physical associationtwo hybrid array--21988832
IntActuniprotkb:P84022uniprotkb:Q134851physical associationtwo hybrid--21988832
IntActuniprotkb:P84022uniprotkb:Q134851physical associationtwo hybrid--27107012
IntActuniprotkb:P84022uniprotkb:Q134851physical associationtwo hybrid array--32296183
IntActuniprotkb:P84022uniprotkb:Q134851physical associationtwo hybrid array--25910212
IntActuniprotkb:P84022uniprotkb:Q134851physical associationtwo hybrid--25502805
IntActuniprotkb:P84022uniprotkb:Q134851physical associationtwo hybrid array--25502805
IntActuniprotkb:P84022uniprotkb:Q134851proximitybioluminescence resonance energy transfer--29997244
IntActuniprotkb:P84022-1uniprotkb:Q134851physical associationtwo hybrid array--31515488
IntActuniprotkb:P84022uniprotkb:Q134851physical associationtwo hybrid array--29892012
IntActuniprotkb:P84022uniprotkb:Q134851physical associationtwo hybrid array--20211142
IntActuniprotkb:P84022uniprotkb:Q134852physical associationtandem affinity purification--18729074
IntActuniprotkb:P84022uniprotkb:Q134852proximityproximity ligation assay--22442258
IntActuniprotkb:P84022uniprotkb:Q134852physical associationbarcode fusion genetics two hybrid--27107012
IntActuniprotkb:P84022uniprotkb:Q134852physical associationvalidated two hybrid--27107012
IntActuniprotkb:P84022uniprotkb:Q134852physical associationtwo hybrid prey pooling approach--32296183
IntActuniprotkb:P84022uniprotkb:Q134852physical associationvalidated two hybrid--32296183
IntActuniprotkb:P84022uniprotkb:Q134852physical associationtwo hybrid bait and prey pooling approach--25910212
IntActuniprotkb:P84022uniprotkb:Q134852physical associationvalidated two hybrid--25910212
IntActuniprotkb:P84022uniprotkb:Q134853associationanti tag coimmunoprecipitation-spoke expansion18729074
IntActuniprotkb:P84022uniprotkb:Q134853physical associationtandem affinity purification-spoke expansion18729074
MINTuniprotkb:P84022uniprotkb:Q134851physical associationtwo hybrid--15231748
MINTuniprotkb:P84022uniprotkb:Q134852physical associationpull down--22045334
MINTuniprotkb:P84022uniprotkb:Q134852physical associationanti tag coimmunoprecipitation--22045334
MINTuniprotkb:P84022uniprotkb:Q134853associationanti tag coimmunoprecipitation-spoke expansion21597466
MINTuniprotkb:P84022uniprotkb:Q134853associationtandem affinity purification-spoke expansion25609649