Interaction Details

Interaction: P53_HUMAN  -  MDM4_HUMAN
Standard Confidence level: 1
Cross-Checked Confidence level: 1
Primary sources: MINT, IntAct, DIP, BioGRID, HPRD
Number of publications: 66

Source Information

SourceInteractor AInteractor BQualityInteraction type(s)Detection method(s)ThroughputExpansionPublications
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionenzymatic studyLow-12393902
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-9226370
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-18485870
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-21088494
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionenzymatic studyLow-17301054
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-20174603
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionenzymatic studyLow-21965653
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionprotein complementation assayLow-22266850
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-21075307
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionprotein complementation assayLow-21075307
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionunspecified methodLow-19153082
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionunspecified methodLow-19305137
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-17875722
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-22807444
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-23028042
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionenzymatic studyLow-23671280
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-24127580
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionenzymatic studyLow-24127580
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-10075736
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-24659749
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-20515689
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionprotein complementation assayLow-25464845
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionunspecified methodLow-26148237
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-25825738
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-27114532
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-28487147
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionunspecified methodLow-18316739
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-25961923
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-29023092
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-10629057
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-22745160
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-31066983
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionfluorescent resonance energy transferHigh-28205554
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41941direct interactionpull downLow-30832340
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-16227609
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-16024788
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-11223036
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942colocalizationimaging techniqueLow-19432880
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-21925390
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-12874296
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-22266850
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-10827196
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-21075307
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-20724842
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-19075013
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942associationx-ray crystallographyLow-19305137
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942associationx-ray crystallographyLow-18677113
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-10608892
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-12370303
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-22374672
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-19521340
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-23028042
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-24445145
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942colocalizationimaging techniqueLow-24445145
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-23946421
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942associationx-ray crystallographyLow-20515689
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-25825738
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-27114532
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-26876197
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-29523541
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-22745160
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-30598450
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-31462704
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41942physical associationaffinity chromatography technologyLow-30672125
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41943physical associationaffinity chromatography technologyHigh-26186194
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41943physical associationaffinity chromatography technologyHigh-25609649
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41943physical associationaffinity chromatography technologyHigh-28514442
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41943physical associationaffinity chromatography technologyHigh-29523541
BioGRIDentrez gene/locuslink:7157entrez gene/locuslink:41943physical associationaffinity chromatography technologyHigh-31152661
DIPuniprotkb:P04637uniprotkb:O151511direct interactionfluorescence polarization spectroscopy--17080083
DIPuniprotkb:P04637uniprotkb:O151511direct interactionisothermal titration calorimetry--19255450
DIPuniprotkb:P04637uniprotkb:O151512physical associationanti bait coimmunoprecipitation--17080083
DIPuniprotkb:P04637uniprotkb:O151513associationanti bait coimmunoprecipitation-spoke expansion17080083
DIPuniprotkb:P04637uniprotkb:O151513associationanti bait coimmunoprecipitation-spoke expansion24667498
HPRD01859040822-in vitro; in vivo--11528400 12393902 15604276 17110929 8895579 9226370
IntActuniprotkb:P04637uniprotkb:O151511physical associationenzyme linked immunosorbent assay--17875722
IntActuniprotkb:P04637uniprotkb:O151512physical associationpull down--17875722
IntActuniprotkb:P04637uniprotkb:O151512physical associationpull down--15916963
IntActuniprotkb:P04637uniprotkb:O151513associationanti tag coimmunoprecipitation-spoke expansion17875722
IntActuniprotkb:P04637uniprotkb:O151513ubiquitination reactionubiquitinase assay-spoke expansion20705607
IntActuniprotkb:P04637-2uniprotkb:O151513associationanti tag coimmunoprecipitation-spoke expansion28514442
MINTuniprotkb:P04637uniprotkb:O151511direct interactionnuclear magnetic resonance--20515689
MINTuniprotkb:P04637uniprotkb:O151511direct interactionisothermal titration calorimetry--20515689
MINTuniprotkb:P04637uniprotkb:O151512physical associationpull down--15604276
MINTuniprotkb:P04637uniprotkb:O151512colocalizationfluorescence microscopy--19521340
MINTuniprotkb:P04637uniprotkb:O151513associationanti bait coimmunoprecipitation-spoke expansion19521340
MINTuniprotkb:P04637uniprotkb:O151513associationtandem affinity purification-spoke expansion25609649