Interaction Details
| Interaction: |
APP
-
BACE1 |
| Standard Confidence level: |
1 |
| Cross-Checked Confidence level: |
1 |
| Primary sources: |
IntAct, UniProt, BioGRID, HPRD |
| Number of publications: |
10 |
Source Information
| Source | Interactor A | Interactor B | Quality | Interaction type(s) | Detection method(s) | Throughput | Expansion | Publications |
| BioGRID | entrez gene/locuslink:351 | entrez gene/locuslink:23621 | 1 | direct interaction | enzymatic study | Low | - | 31996371 |
| BioGRID | entrez gene/locuslink:351 | entrez gene/locuslink:23621 | 2 | physical association | affinity chromatography technology | Low | - | 19251705 |
| BioGRID | entrez gene/locuslink:351 | entrez gene/locuslink:23621 | 2 | physical association | affinity chromatography technology | Low | - | 28869759 |
| HPRD | 00100 | 07255 | 2 | - | in vitro | - | - | 10531052 |
| IntAct | uniprotkb:P05067 | uniprotkb:P56817-1 | 1 | protein cleavage | protease assay | - | - | 10531052 |
| IntAct | uniprotkb:P05067 | uniprotkb:P56817 | 1 | cleavage reaction | cleavage assay | - | - | 22801501 |
| IntAct | uniprotkb:P05067 | uniprotkb:P56817 | 1 | physical association | two hybrid array | - | - | 32814053 |
| IntAct | uniprotkb:P05067 | uniprotkb:P56817-1 | 2 | colocalization | fluorescence microscopy | - | - | 10531052 |
| IntAct | uniprotkb:P05067 | uniprotkb:P56817 | 2 | physical association | two hybrid pooling approach | - | - | 32814053 |
| IntAct | uniprotkb:P05067 | uniprotkb:P56817 | 2 | physical association | validated two hybrid | - | - | 32814053 |
| UniProt | uniprotkb:P05067 | uniprotkb:P56817 | 1 | protein cleavage | protease assay | - | - | 10677483 |
| UniProt | uniprotkb:P05067-4 | uniprotkb:P56817 | 1 | proximity | fluorescent resonance energy transfer | - | - | 16407538 |
| UniProt | uniprotkb:P05067 | uniprotkb:P56817 | 1 | proximity | fluorescent resonance energy transfer | - | - | 30538620 |
| UniProt | uniprotkb:P05067 | uniprotkb:P56817 | 1 | physical association | two hybrid | - | - | 12901838 |
| UniProt | uniprotkb:P05067 | uniprotkb:P56817 | 2 | colocalization | confocal microscopy | - | - | 10677483 |
| UniProt | uniprotkb:P05067 | uniprotkb:P56817 | 3 | proximity | fluorescent resonance energy transfer | - | spoke expansion | 30538620 |