Publication Details

Pubmed20124408
Title: SCH529074, a small molecule activator of mutant p53, which binds p53 DNA binding domain (DBD), restores growth-suppressive function to mutant p53 and interrupts HDM2-mediated ubiquitination of wild type p53.
Year: 2010
DOI: https://doi.org/10.1074/jbc.M109.083469
First Author: Demma
Experimental setup: enzymatic study (Biogrid)
pull down (Biogrid)
Throughput: Low Throughput (Biogrid)

Interactions

2 interactions
InteractorPartnerSourcesLink
P53_HUMANMDM2_HUMANBioGRIDdetails
UB2D1_HUMANMDM2_HUMANBioGRIDdetails