Publication Details

Pubmed24163370
Title: The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.
Year: 2013
DOI: https://doi.org/10.1074/jbc.M113.472076
First Author: Lu
Experimental setup: affinity chromatography technology (Biogrid)
biochemical (Biogrid)
enzymatic study (Biogrid)
pull down (Biogrid)
Throughput: High Throughput (Biogrid)
Low Throughput (Biogrid)

Interactions

286 interactions
InteractorPartnerSourcesLink
CDC16_HUMANAPC11_HUMANBioGRIDdetails
CCNB1_HUMANFZR1_HUMANBioGRIDdetails
ANC2_HUMANAPC11_HUMANBioGRIDdetails
CDC27_HUMANAPC11_HUMANBioGRIDdetails
HECW2_HUMANFZR1_HUMANBioGRIDdetails
APC11_HUMANCDC23_HUMANBioGRIDdetails
HECW2_HUMANHECW1_HUMANBioGRIDdetails
HECW2_HUMANRAI1_HUMANBioGRIDdetails
HECW2_HUMANUSP9X_HUMANBioGRIDdetails
HECW2_HUMANINCE_HUMANBioGRIDdetails
HECW2_HUMANDIDO1_HUMANBioGRIDdetails
HECW2_HUMANGRN_HUMANBioGRIDdetails
HECW2_HUMANDRG1_HUMANBioGRIDdetails
HECW2_HUMANADT3_HUMANBioGRIDdetails
HECW2_HUMANGGCT_HUMANBioGRIDdetails
HECW2_HUMANCDC27_HUMANBioGRIDdetails
HECW2_HUMANKDM4D_HUMANBioGRIDdetails
HECW2_HUMANNEP1_HUMANBioGRIDdetails
HECW2_HUMANF120B_HUMANBioGRIDdetails
HECW2_HUMANCALL3_HUMANBioGRIDdetails
HECW2_HUMANCTRO_HUMANBioGRIDdetails
HECW2_HUMANRAD54_HUMANBioGRIDdetails
HECW2_HUMANZC3HE_HUMANBioGRIDdetails
HECW2_HUMANRL24_HUMANBioGRIDdetails
HECW2_HUMANYTHD3_HUMANBioGRIDdetails
HECW2_HUMANCDT1_HUMANBioGRIDdetails
HECW2_HUMANCDC23_HUMANBioGRIDdetails
HECW2_HUMANCBX4_HUMANBioGRIDdetails
HECW2_HUMANENAH_HUMANBioGRIDdetails
HECW2_HUMANPKN3_HUMANBioGRIDdetails
HECW2_HUMANZZZ3_HUMANBioGRIDdetails
HECW2_HUMANBAIP2_HUMANBioGRIDdetails
HECW2_HUMANBI2L1_HUMANBioGRIDdetails
HECW2_HUMANNSE4A_HUMANBioGRIDdetails
HECW2_HUMANPRDX2_HUMANBioGRIDdetails
HECW2_HUMANMARK1_HUMANBioGRIDdetails
HECW2_HUMANTRIM3_HUMANBioGRIDdetails
HECW2_HUMANSAMD1_HUMANBioGRIDdetails
HECW2_HUMANDMAP1_HUMANBioGRIDdetails
HECW2_HUMANNPL4_HUMANBioGRIDdetails
HECW2_HUMANRPOM_HUMANBioGRIDdetails
HECW2_HUMANT2FB_HUMANBioGRIDdetails
HECW2_HUMANRBM28_HUMANBioGRIDdetails
HECW2_HUMANSPB12_HUMANBioGRIDdetails
HECW2_HUMANCHAP1_HUMANBioGRIDdetails
HECW2_HUMANDOPD_HUMANBioGRIDdetails
HECW2_HUMANERPG3_HUMANBioGRIDdetails
HECW2_HUMANERCC6_HUMANBioGRIDdetails
HECW2_HUMANTIRR_HUMANBioGRIDdetails
HECW2_HUMANRT09_HUMANBioGRIDdetails
HECW2_HUMANAMOL1_HUMANBioGRIDdetails
HECW2_HUMANERF1_HUMANBioGRIDdetails
HECW2_HUMANWIZ_HUMANBioGRIDdetails
HECW2_HUMANCALM1_HUMANBioGRIDdetails
HECW2_HUMANCALM2_HUMANBioGRIDdetails
HECW2_HUMANCALM3_HUMANBioGRIDdetails
HECW2_HUMANTECR_HUMANBioGRIDdetails
HECW2_HUMANCDC20_HUMANBioGRIDdetails
HECW2_HUMANRAD21_HUMANBioGRIDdetails
HECW2_HUMANELAV1_HUMANBioGRIDdetails
HECW2_HUMANGRB10_HUMANBioGRIDdetails
HECW2_HUMANMBIP1_HUMANBioGRIDdetails
HECW2_HUMANRCL1_HUMANBioGRIDdetails
HECW2_HUMANSO4C1_HUMANBioGRIDdetails
HECW2_HUMANTBG1_HUMANBioGRIDdetails
HECW2_HUMANMEIOB_HUMANBioGRIDdetails
HECW2_HUMANF133B_HUMANBioGRIDdetails
HECW2_HUMANMA7D1_HUMANBioGRIDdetails
HECW2_HUMANMORC2_HUMANBioGRIDdetails
HECW2_HUMANPPIB_HUMANBioGRIDdetails
HECW2_HUMANALKB5_HUMANBioGRIDdetails
HECW2_HUMANASTE1_HUMANBioGRIDdetails
HECW2_HUMANSRPK1_HUMANBioGRIDdetails
HECW2_HUMANS35E1_HUMANBioGRIDdetails
HECW2_HUMANRU2B_HUMANBioGRIDdetails
HECW2_HUMANAPC4_HUMANBioGRIDdetails
HECW2_HUMANCABIN_HUMANBioGRIDdetails
HECW2_HUMANCSK21_HUMANBioGRIDdetails
HECW2_HUMANRING1_HUMANBioGRIDdetails
HECW2_HUMANDHB12_HUMANBioGRIDdetails
HECW2_HUMANLACRT_HUMANBioGRIDdetails
HECW2_HUMANCHTOP_HUMANBioGRIDdetails
HECW2_HUMANGSK3B_HUMANBioGRIDdetails
HECW2_HUMANSRCAP_HUMANBioGRIDdetails
HECW2_HUMANKMT2A_HUMANBioGRIDdetails
HECW2_HUMANSPNDC_HUMANBioGRIDdetails
HECW2_HUMANGPAM1_HUMANBioGRIDdetails
HECW2_HUMANLMNB1_HUMANBioGRIDdetails
HECW2_HUMANLAMB1_HUMANBioGRIDdetails
HECW2_HUMANLAR4B_HUMANBioGRIDdetails
HECW2_HUMANMED16_HUMANBioGRIDdetails
HECW2_HUMANMTAP2_HUMANBioGRIDdetails
HECW2_HUMANPXDN_HUMANBioGRIDdetails
HECW2_HUMANPSB1_HUMANBioGRIDdetails
HECW2_HUMANPKCB1_HUMANBioGRIDdetails
HECW2_HUMANPYC_HUMANBioGRIDdetails
HECW2_HUMANPAK4_HUMANBioGRIDdetails
HECW2_HUMANSNW1_HUMANBioGRIDdetails
HECW2_HUMANTAAR2_HUMANBioGRIDdetails
HECW2_HUMANU3IP2_HUMANBioGRIDdetails
HECW2_HUMANVP33B_HUMANBioGRIDdetails
HECW2_HUMANZMAT4_HUMANBioGRIDdetails
HECW2_HUMANZN207_HUMANBioGRIDdetails
HECW2_HUMANCBX3_HUMANBioGRIDdetails
HECW2_HUMAN3MG_HUMANBioGRIDdetails
HECW2_HUMANMORC4_HUMANBioGRIDdetails
HECW2_HUMANMAZ_HUMANBioGRIDdetails
HECW2_HUMANSF3A2_HUMANBioGRIDdetails
HECW2_HUMANTRM2A_HUMANBioGRIDdetails
HECW2_HUMANACL6A_HUMANBioGRIDdetails
HECW2_HUMANBIRC1_HUMANBioGRIDdetails
HECW2_HUMANCATIN_HUMANBioGRIDdetails
HECW2_HUMANDNJC8_HUMANBioGRIDdetails
HECW2_HUMANEXOS7_HUMANBioGRIDdetails
HECW2_HUMANIMA5_HUMANBioGRIDdetails
HECW2_HUMANNO40_HUMANBioGRIDdetails
HECW2_HUMANPHC2_HUMANBioGRIDdetails
HECW2_HUMANFRG1_HUMANBioGRIDdetails
HECW2_HUMANSENP3_HUMANBioGRIDdetails
HECW2_HUMANAPC5_HUMANBioGRIDdetails
HECW2_HUMANANXA1_HUMANBioGRIDdetails
HECW2_HUMANCDC16_HUMANBioGRIDdetails
HECW2_HUMANCDYL_HUMANBioGRIDdetails
HECW2_HUMANF120A_HUMANBioGRIDdetails
HECW2_HUMANTRI25_HUMANBioGRIDdetails
HECW2_HUMANRING2_HUMANBioGRIDdetails
HECW2_HUMANALDOC_HUMANBioGRIDdetails
HECW2_HUMANBGAT_HUMANBioGRIDdetails
HECW2_HUMANMED12_HUMANBioGRIDdetails
HECW2_HUMANMCES_HUMANBioGRIDdetails
HECW2_HUMANNELFA_HUMANBioGRIDdetails
HECW2_HUMANNOSIP_HUMANBioGRIDdetails
HECW2_HUMANPWP2_HUMANBioGRIDdetails
HECW2_HUMANPHF6_HUMANBioGRIDdetails
HECW2_HUMANPI51A_HUMANBioGRIDdetails
HECW2_HUMANDHX36_HUMANBioGRIDdetails
HECW2_HUMANLS14A_HUMANBioGRIDdetails
HECW2_HUMANPOP1_HUMANBioGRIDdetails
HECW2_HUMANMRM3_HUMANBioGRIDdetails
HECW2_HUMANSRS10_HUMANBioGRIDdetails
HECW2_HUMANCHK1_HUMANBioGRIDdetails
HECW2_HUMANPKN2_HUMANBioGRIDdetails
HECW2_HUMAN3BP1_HUMANBioGRIDdetails
HECW2_HUMANSPAG5_HUMANBioGRIDdetails
HECW2_HUMANSPHK2_HUMANBioGRIDdetails
HECW2_HUMANSMHD1_HUMANBioGRIDdetails
HECW2_HUMANTAF5L_HUMANBioGRIDdetails
HECW2_HUMANWDR36_HUMANBioGRIDdetails
HECW2_HUMANWBP11_HUMANBioGRIDdetails
HECW2_HUMANZN638_HUMANBioGRIDdetails
HECW2_HUMANHACD3_HUMANBioGRIDdetails
HECW2_HUMANXRN1_HUMANBioGRIDdetails
HECW2_HUMANARP5_HUMANBioGRIDdetails
HECW2_HUMANASCC3_HUMANBioGRIDdetails
HECW2_HUMANSAHH_HUMANBioGRIDdetails
HECW2_HUMANARF4_HUMANBioGRIDdetails
HECW2_HUMANAFF4_HUMANBioGRIDdetails
HECW2_HUMANAPC1_HUMANBioGRIDdetails
HECW2_HUMANDDX24_HUMANBioGRIDdetails
HECW2_HUMANCTBL1_HUMANBioGRIDdetails
HECW2_HUMANKCTD6_HUMANBioGRIDdetails
HECW2_HUMANCAR14_HUMANBioGRIDdetails
HECW2_HUMANCNO10_HUMANBioGRIDdetails
HECW2_HUMANCENPF_HUMANBioGRIDdetails
HECW2_HUMANCEP55_HUMANBioGRIDdetails
HECW2_HUMANKGP1_HUMANBioGRIDdetails
HECW2_HUMANHUS1_HUMANBioGRIDdetails
HECW2_HUMANCPSF2_HUMANBioGRIDdetails
HECW2_HUMANCSTF3_HUMANBioGRIDdetails
HECW2_HUMANCOF1_HUMANBioGRIDdetails
HECW2_HUMANKCRU_HUMANBioGRIDdetails
HECW2_HUMANCRTC2_HUMANBioGRIDdetails
HECW2_HUMANCCNA1_HUMANBioGRIDdetails
HECW2_HUMANCCNK_HUMANBioGRIDdetails
HECW2_HUMANCYC_HUMANBioGRIDdetails
HECW2_HUMANCYFP1_HUMANBioGRIDdetails
HECW2_HUMANCYTSB_HUMANBioGRIDdetails
HECW2_HUMANDCNL5_HUMANBioGRIDdetails
HECW2_HUMANDRS7B_HUMANBioGRIDdetails
HECW2_HUMANFSBP_HUMANBioGRIDdetails
HECW2_HUMANRA54B_HUMANBioGRIDdetails
HECW2_HUMANKIN17_HUMANBioGRIDdetails
HECW2_HUMANRPB2_HUMANBioGRIDdetails
HECW2_HUMANDNJA2_HUMANBioGRIDdetails
HECW2_HUMANDYSF_HUMANBioGRIDdetails
HECW2_HUMANEP400_HUMANBioGRIDdetails
HECW2_HUMANRBBP6_HUMANBioGRIDdetails
HECW2_HUMANEF1D_HUMANBioGRIDdetails
HECW2_HUMANNTH_HUMANBioGRIDdetails
HECW2_HUMANEIF3H_HUMANBioGRIDdetails
HECW2_HUMANEIF3I_HUMANBioGRIDdetails
HECW2_HUMANEIF3J_HUMANBioGRIDdetails
HECW2_HUMANECM1_HUMANBioGRIDdetails
HECW2_HUMANCAPZB_HUMANBioGRIDdetails
HECW2_HUMANSP20H_HUMANBioGRIDdetails
HECW2_HUMANSHCAF_HUMANBioGRIDdetails
HECW2_HUMANFOXK2_HUMANBioGRIDdetails
HECW2_HUMANLEG7_HUMANBioGRIDdetails
HECW2_HUMANGCP2_HUMANBioGRIDdetails
HECW2_HUMANGCP3_HUMANBioGRIDdetails
HECW2_HUMANGATD1_HUMANBioGRIDdetails
HECW2_HUMANGLCI1_HUMANBioGRIDdetails
HECW2_HUMANHS105_HUMANBioGRIDdetails
HECW2_HUMANENR1_HUMANBioGRIDdetails
HECW2_HUMANHM20A_HUMANBioGRIDdetails
HECW2_HUMANKAT2A_HUMANBioGRIDdetails
HECW2_HUMANANR65_HUMANBioGRIDdetails
HECW2_HUMANHROB_HUMANBioGRIDdetails
HECW2_HUMANINT4_HUMANBioGRIDdetails
HECW2_HUMANE2AK2_HUMANBioGRIDdetails
HECW2_HUMANLAMC1_HUMANBioGRIDdetails
HECW2_HUMANAVL9_HUMANBioGRIDdetails
HECW2_HUMANLMBL3_HUMANBioGRIDdetails
HECW2_HUMANACSL4_HUMANBioGRIDdetails
HECW2_HUMANLYNX1_HUMANBioGRIDdetails
HECW2_HUMANGMPPA_HUMANBioGRIDdetails
HECW2_HUMANMED14_HUMANBioGRIDdetails
HECW2_HUMANMAP11_HUMANBioGRIDdetails
HECW2_HUMANMECP2_HUMANBioGRIDdetails
HECW2_HUMANMILK1_HUMANBioGRIDdetails
HECW2_HUMANMACF1_HUMANBioGRIDdetails
HECW2_HUMANMAP1S_HUMANBioGRIDdetails
HECW2_HUMANTOM34_HUMANBioGRIDdetails
HECW2_HUMANC1TM_HUMANBioGRIDdetails
HECW2_HUMANSMAD5_HUMANBioGRIDdetails
HECW2_HUMANMOB1A_HUMANBioGRIDdetails
HECW2_HUMANESCO1_HUMANBioGRIDdetails
HECW2_HUMANSIR5_HUMANBioGRIDdetails
HECW2_HUMANNCKP5_HUMANBioGRIDdetails
HECW2_HUMANNCOA5_HUMANBioGRIDdetails
HECW2_HUMANSEH1_HUMANBioGRIDdetails
HECW2_HUMANNTPCR_HUMANBioGRIDdetails
HECW2_HUMANNUDC1_HUMANBioGRIDdetails
HECW2_HUMANOSBL8_HUMANBioGRIDdetails
HECW2_HUMANGIPC1_HUMANBioGRIDdetails
HECW2_HUMANPX11B_HUMANBioGRIDdetails
HECW2_HUMANPM34_HUMANBioGRIDdetails
HECW2_HUMANDHB4_HUMANBioGRIDdetails
HECW2_HUMANPHF3_HUMANBioGRIDdetails
HECW2_HUMANEGFLA_HUMANBioGRIDdetails
HECW2_HUMANPA1B2_HUMANBioGRIDdetails
HECW2_HUMANKAT8_HUMANBioGRIDdetails
HECW2_HUMANPSA7_HUMANBioGRIDdetails
HECW2_HUMANPSB3_HUMANBioGRIDdetails
HECW2_HUMANPSB7_HUMANBioGRIDdetails
HECW2_HUMANANGE2_HUMANBioGRIDdetails
HECW2_HUMANANM5_HUMANBioGRIDdetails
HECW2_HUMANLS14B_HUMANBioGRIDdetails
HECW2_HUMANPB1_HUMANBioGRIDdetails
HECW2_HUMANS10AE_HUMANBioGRIDdetails
HECW2_HUMANMOS_HUMANBioGRIDdetails
HECW2_HUMANPNPH_HUMANBioGRIDdetails
HECW2_HUMANASXL2_HUMANBioGRIDdetails
HECW2_HUMANRB15B_HUMANBioGRIDdetails
HECW2_HUMANRSPH9_HUMANBioGRIDdetails
HECW2_HUMANRADIL_HUMANBioGRIDdetails
HECW2_HUMANREN3B_HUMANBioGRIDdetails
HECW2_HUMANRTL9_HUMANBioGRIDdetails
HECW2_HUMANRNAS4_HUMANBioGRIDdetails
HECW2_HUMANKS6A4_HUMANBioGRIDdetails
HECW2_HUMANELOA2_HUMANBioGRIDdetails
HECW2_HUMANCTR9_HUMANBioGRIDdetails
HECW2_HUMANRBM42_HUMANBioGRIDdetails
HECW2_HUMANSCAPE_HUMANBioGRIDdetails
HECW2_HUMANSRBD1_HUMANBioGRIDdetails
HECW2_HUMANSCML2_HUMANBioGRIDdetails
HECW2_HUMANSPAST_HUMANBioGRIDdetails
HECW2_HUMANTALD3_HUMANBioGRIDdetails
HECW2_HUMANAP2A_HUMANBioGRIDdetails
HECW2_HUMANSP2_HUMANBioGRIDdetails
HECW2_HUMANTAD2B_HUMANBioGRIDdetails
HECW2_HUMANNFX1_HUMANBioGRIDdetails
HECW2_HUMANDUS3L_HUMANBioGRIDdetails
HECW2_HUMANTSC2_HUMANBioGRIDdetails
HECW2_HUMANUBP10_HUMANBioGRIDdetails
HECW2_HUMANUBP21_HUMANBioGRIDdetails
HECW2_HUMANMIO_HUMANBioGRIDdetails
HECW2_HUMANYETS4_HUMANBioGRIDdetails
HECW2_HUMANZBTB9_HUMANBioGRIDdetails
HECW2_HUMANZC3H3_HUMANBioGRIDdetails
HECW2_HUMANZ3H7B_HUMANBioGRIDdetails
HECW2_HUMANZN579_HUMANBioGRIDdetails
HECW2_HUMANZF64B_HUMANBioGRIDdetails
HECW2_HUMANZRAB3_HUMANBioGRIDdetails
HECW2_HUMANZSWM6_HUMANBioGRIDdetails
HECW2_HUMANZP3_HUMANBioGRIDdetails